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Mycobacterium leprae intracellular survival relies on cholesterol accumulation in infected macrophages: a potential target for new drugs for leprosy treatment.
Mattos KA, Oliveira VC, Berrêdo-Pinho M, Amaral JJ, Antunes LC, Melo RC, Acosta CC, Moura DF, Olmo R, Han J, Rosa PS, Almeida PE, Finlay BB, Borchers CH, Sarno EN, Bozza PT, Atella GC, Pessolani MC. Mattos KA, et al. Cell Microbiol. 2014 Jun;16(6):797-815. doi: 10.1111/cmi.12279. Epub 2014 Mar 21. Cell Microbiol. 2014. PMID: 24552180 Free PMC article.
Reductive Power Generated by Mycobacterium leprae Through Cholesterol Oxidation Contributes to Lipid and ATP Synthesis.
Rosa TLSA, Marques MAM, DeBoard Z, Hutchins K, Silva CAA, Montague CR, Yuan T, Amaral JJ, Atella GC, Rosa PS, Mattos KA, VanderVen BC, Lahiri R, Sampson NS, Brennan PJ, Belisle JT, Pessolani MCV, Berrêdo-Pinho M. Rosa TLSA, et al. Among authors: mattos ka. Front Cell Infect Microbiol. 2021 Jul 28;11:709972. doi: 10.3389/fcimb.2021.709972. eCollection 2021. Front Cell Infect Microbiol. 2021. PMID: 34395315 Free PMC article.
Corrigendum: Reductive Power Generated by Mycobacterium leprae Through Cholesterol Oxidation Contributes to Lipid and ATP Synthesis.
Rosa TLSA, Marques MAM, DeBoard Z, Hutchins K, Silva CAA, Montague CR, Yuan T, Amaral JJ, Atella GC, Rosa PS, Mattos KA, VanderVen BC, Lahiri R, Sampson NS, Brennan PJ, Belisle JT, Pessolani MCV, Berrêdo-Pinho M. Rosa TLSA, et al. Among authors: mattos ka. Front Cell Infect Microbiol. 2021 Sep 28;11:765326. doi: 10.3389/fcimb.2021.765326. eCollection 2021. Front Cell Infect Microbiol. 2021. PMID: 34650934 Free PMC article.
PGL I expression in live bacteria allows activation of a CD206/PPARγ cross-talk that may contribute to successful Mycobacterium leprae colonization of peripheral nerves.
Díaz Acosta CC, Dias AA, Rosa TLSA, Batista-Silva LR, Rosa PS, Toledo-Pinto TG, Costa FDMR, Lara FA, Rodrigues LS, Mattos KA, Sarno EN, Bozza PT, Guilhot C, de Berrêdo-Pinho M, Pessolani MCV. Díaz Acosta CC, et al. Among authors: mattos ka. PLoS Pathog. 2018 Jul 6;14(7):e1007151. doi: 10.1371/journal.ppat.1007151. eCollection 2018 Jul. PLoS Pathog. 2018. PMID: 29979790 Free PMC article.
Metabonomics reveals drastic changes in anti-inflammatory/pro-resolving polyunsaturated fatty acids-derived lipid mediators in leprosy disease.
Amaral JJ, Antunes LC, de Macedo CS, Mattos KA, Han J, Pan J, Candéa AL, Henriques Md, Ribeiro-Alves M, Borchers CH, Sarno EN, Bozza PT, Finlay BB, Pessolani MC. Amaral JJ, et al. Among authors: mattos ka. PLoS Negl Trop Dis. 2013 Aug 15;7(8):e2381. doi: 10.1371/journal.pntd.0002381. eCollection 2013. PLoS Negl Trop Dis. 2013. PMID: 23967366 Free PMC article.
Differential TLR2 downstream signaling regulates lipid metabolism and cytokine production triggered by Mycobacterium bovis BCG infection.
Almeida PE, Roque NR, Magalhães KG, Mattos KA, Teixeira L, Maya-Monteiro C, Almeida CJ, Castro-Faria-Neto HC, Ryffel B, Quesniaux VF, Bozza PT. Almeida PE, et al. Among authors: mattos ka. Biochim Biophys Acta. 2014 Jan;1841(1):97-107. doi: 10.1016/j.bbalip.2013.10.008. Epub 2013 Oct 10. Biochim Biophys Acta. 2014. PMID: 24120921
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