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Precision diabetes: Lessons learned from maturity-onset diabetes of the young (MODY).
Tosur M, Philipson LH. Tosur M, et al. J Diabetes Investig. 2022 Sep;13(9):1465-1471. doi: 10.1111/jdi.13860. Epub 2022 Jun 16. J Diabetes Investig. 2022. PMID: 35638342 Free PMC article. Review.
Despite its high clinical impact, 50-90% of MODY cases are estimated to be misdiagnosed as type 1 or type 2 diabetes. Although there are many clinical features suggestive of MODY diagnosis, there is no single clinical criterion. ...
Despite its high clinical impact, 50-90% of MODY cases are estimated to be misdiagnosed as type 1 or type 2 diabetes. Although …
Maturity-onset diabetes of the young and pregnancy.
Kauffmann A, Jørgensen IL, Thuesen AC, Ringholm L, Clausen TD, Mathiesen ER, Hansen T, Damm P. Kauffmann A, et al. Ugeskr Laeger. 2023 May 22;185(21):V02230067. Ugeskr Laeger. 2023. PMID: 37264885 Free article. Review. Danish.
Maturity-onset diabetes of the young (MODY) is a group of hereditary monogenetic forms of diabetes. MODY accounts for 1-3% of all persons with diabetes but is often undiagnosed or misdiagnosed as type 1 diabetes, type 2 diab …
Maturity-onset diabetes of the young (MODY) is a group of hereditary monogenetic forms of diabetes …
Tunisian Maturity-Onset Diabetes of the Young: A Short Review and a New Molecular and Clinical Investigation.
Moalla M, Safi W, Babiker Mansour M, Hadj Kacem M, Mahfood M, Abid M, Kammoun T, Hachicha M, Mnif-Feki M, Hadj Kacem F, Hadj Kacem H. Moalla M, et al. Front Endocrinol (Lausanne). 2021 Jul 29;12:684018. doi: 10.3389/fendo.2021.684018. eCollection 2021. Front Endocrinol (Lausanne). 2021. PMID: 34393998 Free PMC article. Review.
INTRODUCTION/AIMS: Maturity-Onset Diabetes of the Young (MODY) is a monogenic non-autoimmune diabetes with 14 different genetic forms. ...CONCLUSIONS: The most appropriate patients were selected, following a strict clinical screening appr …
INTRODUCTION/AIMS: Maturity-Onset Diabetes of the Young (MODY) is a monogenic non-autoimmune diabe …
Maturity onset diabetes of the young: Seek and you will find.
Heuvel-Borsboom H, de Valk HW, Losekoot M, Westerink J. Heuvel-Borsboom H, et al. Neth J Med. 2016 Jun;74(5):193-200. Neth J Med. 2016. PMID: 27323672 Free article. Review.
Maturity onset diabetes of the young (MODY) is a monogenic, autosomal dominant form of diabetes characterised by mutations in genes resulting in dysfunction of pancreatic beta-cells and subsequent insulin production. We present a family w …
Maturity onset diabetes of the young (MODY) is a monogenic, autosomal dominant form of diabetes ch …
Maturity-onset diabetes of the young (MODY) - in search of ideal diagnostic criteria and precise treatment.
Zečević K, Volčanšek Š, Katsiki N, Rizzo M, Milardović TM, Stoian AP, Banach M, Muzurović E. Zečević K, et al. Prog Cardiovasc Dis. 2024 Jul-Aug;85:14-25. doi: 10.1016/j.pcad.2024.03.004. Epub 2024 Mar 19. Prog Cardiovasc Dis. 2024. PMID: 38513726 Review.
Maturity-onset diabetes of the young (MODY) is a spectrum of clinically heterogenous forms of monogenic diabetes mellitus characterized by autosomal dominant inheritance, onset at a young age, and absence of pancreatic islets autoimmunity …
Maturity-onset diabetes of the young (MODY) is a spectrum of clinically heterogenous forms of mono …
Maturity onset diabetes of the young (MODY).
Fajans SS, Bell GI, Bowden DW, Halter JB, Polonsky KS. Fajans SS, et al. Diabet Med. 1996 Sep;13(9 Suppl 6):S90-5. Diabet Med. 1996. PMID: 8894490 Free article. Review.
MODY is a sub-type of NIDDM. It is characterized by an early age of onset and autosomal dominant mode of inheritance. ...
MODY is a sub-type of NIDDM. It is characterized by an early age of onset and autosomal dominant mode of inheritance. ...
Diagnosis of maturity-onset diabetes of the young in the pediatric diabetes clinic.
Hattersley AT. Hattersley AT. J Pediatr Endocrinol Metab. 2000;13 Suppl 6:1411-7. doi: 10.1515/jpem-2000-s615. J Pediatr Endocrinol Metab. 2000. PMID: 11202217 Review.
The subgroups that result in non-insulin-dependent DM in children are as follows: the 'honeymoon' phase of type 1 DM, type 2 DM, genetic syndromes accompanied by DM, and maturity-onset diabetes of the young (MODY). ...In the …
The subgroups that result in non-insulin-dependent DM in children are as follows: the 'honeymoon' phase of type 1 DM, type 2 D …
Diabetes at the crossroads: relevance of disease classification to pathophysiology and treatment.
Leslie RD, Palmer J, Schloot NC, Lernmark A. Leslie RD, et al. Diabetologia. 2016 Jan;59(1):13-20. doi: 10.1007/s00125-015-3789-z. Diabetologia. 2016. PMID: 26498592 Review.
Our broad understanding of the distinction between the two major types, type 1 diabetes mellitus and type 2 diabetes mellitus, are based on these factors, but it has become apparent that they do not precisely capture the different disease forms. Indeed, both major t …
Our broad understanding of the distinction between the two major types, type 1 diabetes mellitus and type 2 diabetes mellitus, …
Personalized medicine in diabetes: the role of 'omics' and biomarkers.
Pearson ER. Pearson ER. Diabet Med. 2016 Jun;33(6):712-7. doi: 10.1111/dme.13075. Diabet Med. 2016. PMID: 26802434 Free PMC article. Review.
The field of pharmacogenetics is now yielding clinically important results, with three examples outlined: sulphonylurea sensitivity in patients with HNF1A maturity-onset diabetes of the young; sulphonylurea sensitivity in patients with …
The field of pharmacogenetics is now yielding clinically important results, with three examples outlined: sulphonylurea sensitivity in patie …
Pharmacogenetics and target identification in diabetes.
Pearson ER. Pearson ER. Curr Opin Genet Dev. 2018 Jun;50:68-73. doi: 10.1016/j.gde.2018.02.005. Epub 2018 Feb 24. Curr Opin Genet Dev. 2018. PMID: 29486427 Review.
This can be seen with dramatic impact on clinical care, in patients with genetic forms of diabetes such as Maturity Onset Diabetes of the Young caused by HNF1A mutations, and Neonatal diabetes due to activating mutations in ABCC8 or KCNJ1 …
This can be seen with dramatic impact on clinical care, in patients with genetic forms of diabetes such as Maturity Onset D …
26 results