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Design and Comparative Evaluation of the Anticonvulsant Profile, Carbonic-Anhydrate Inhibition and Teratogenicity of Novel Carbamate Derivatives of Branched Aliphatic Carboxylic Acids with 4-Aminobenzensulfonamide.
Neurochem Res. 2017 Jul;42(7):1972-1982. doi: 10.1007/s11064-017-2216-x. Epub 2017 Mar 9.
Neurochem Res. 2017.
PMID: 28275953
Enantioselective pharmacodynamic and pharmacokinetic analysis of two chiral CNS-active carbamate derivatives of valproic acid.
Shekh-Ahmad T, Mawasi H, McDonough JH, Finnell RH, Wlodarczyk BJ, Yavin E, Bialer M.
Shekh-Ahmad T, et al. Among authors: mawasi h.
Epilepsia. 2014 Dec;55(12):1944-52. doi: 10.1111/epi.12857. Epub 2014 Nov 29.
Epilepsia. 2014.
PMID: 25442425
Free article.
Clinical Trial.
Item in Clipboard
Pharmacodynamic and pharmacokinetic analysis of CNS-active constitutional isomers of valnoctamide and sec-butylpropylacetamide--Amide derivatives of valproic acid.
Mawasi H, Shekh-Ahmad T, Finnell RH, Wlodarczyk BJ, Bialer M.
Mawasi H, et al.
Epilepsy Behav. 2015 May;46:72-8. doi: 10.1016/j.yebeh.2015.02.040. Epub 2015 Apr 8.
Epilepsy Behav. 2015.
PMID: 25863940
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Design and comparative anticonvulsant activity assessment of CNS-active alkyl-carbamoyl imidazole derivatives.
Mawasi H, Bibi D, Bialer M.
Mawasi H, et al.
Bioorg Med Chem. 2016 Sep 15;24(18):4246-4253. doi: 10.1016/j.bmc.2016.07.018. Epub 2016 Jul 12.
Bioorg Med Chem. 2016.
PMID: 27469980
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The potential of sec-butylpropylacetamide (SPD) and valnoctamide and their individual stereoisomers in status epilepticus.
Shekh-Ahmad T, Mawasi H, McDonough JH, Yagen B, Bialer M.
Shekh-Ahmad T, et al. Among authors: mawasi h.
Epilepsy Behav. 2015 Aug;49:298-302. doi: 10.1016/j.yebeh.2015.04.012. Epub 2015 May 13.
Epilepsy Behav. 2015.
PMID: 25979572
Review.
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Pharmacokinetic-Pharmacodynamic Correlation and Brain Penetration of sec-Butylpropylacetamide, a New CNS Drug Possessing Unique Activity against Status Epilepticus.
Mawasi H, Bibi D, Shekh-Ahmad T, Shaul C, Blotnik S, Bialer M.
Mawasi H, et al.
Mol Pharm. 2016 Jul 5;13(7):2492-6. doi: 10.1021/acs.molpharmaceut.6b00221. Epub 2016 Jun 2.
Mol Pharm. 2016.
PMID: 27218460
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Mitochondrial Liver Toxicity of Valproic Acid and Its Acid Derivatives Is Related to Inhibition of α-Lipoamide Dehydrogenase.
Kudin AP, Mawasi H, Eisenkraft A, Elger CE, Bialer M, Kunz WS.
Kudin AP, et al. Among authors: mawasi h.
Int J Mol Sci. 2017 Sep 6;18(9):1912. doi: 10.3390/ijms18091912.
Int J Mol Sci. 2017.
PMID: 28878165
Free PMC article.
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