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Interactions between the oestrogen and insulin-like growth factor signalling pathways in the control of breast epithelial cell proliferation.
Westley BR, Clayton SJ, Daws MR, Molloy CA, May FE. Westley BR, et al. Among authors: may fe. Biochem Soc Symp. 1998;63:35-44. Biochem Soc Symp. 1998. PMID: 9513709 Review.
Homodimerization and hetero-oligomerization of the single-domain trefoil protein pNR-2/pS2 through cysteine 58.
Chadwick MP, Westley BR, May FE. Chadwick MP, et al. Among authors: may fe. Biochem J. 1997 Oct 1;327 ( Pt 1)(Pt 1):117-23. doi: 10.1042/bj3270117. Biochem J. 1997. PMID: 9355742 Free PMC article.
Dramatic diurnal variation in the concentration of the human trefoil peptide TFF2 in gastric juice.
Semple JI, Newton JL, Westley BR, May FE. Semple JI, et al. Among authors: may fe. Gut. 2001 May;48(5):648-55. doi: 10.1136/gut.48.5.648. Gut. 2001. PMID: 11302963 Free PMC article.
The human two domain trefoil protein, TFF2, is glycosylated in vivo in the stomach.
May FE, Semple JI, Newton JL, Westley BR. May FE, et al. Gut. 2000 Apr;46(4):454-9. doi: 10.1136/gut.46.4.454. Gut. 2000. PMID: 10716671 Free PMC article.
The trefoil factor interacting protein TFIZ1 binds the trefoil protein TFF1 preferentially in normal gastric mucosal cells but the co-expression of these proteins is deregulated in gastric cancer.
May FE, Griffin SM, Westley BR. May FE, et al. Int J Biochem Cell Biol. 2009 Mar;41(3):632-40. doi: 10.1016/j.biocel.2008.07.015. Epub 2008 Aug 3. Int J Biochem Cell Biol. 2009. PMID: 18722547 Free PMC article.
The estrogen-regulated protein, TFF1, stimulates migration of human breast cancer cells.
Prest SJ, May FE, Westley BR. Prest SJ, et al. Among authors: may fe. FASEB J. 2002 Apr;16(6):592-4. doi: 10.1096/fj.01-0498fje. FASEB J. 2002. PMID: 11919164
Expression and motogenic activity of TFF2 in human breast cancer cells.
May FE, Semple JI, Prest SJ, Westley BR. May FE, et al. Peptides. 2004 May;25(5):865-72. doi: 10.1016/j.peptides.2003.12.024. Peptides. 2004. PMID: 15177883
The closely related estrogen-regulated trefoil proteins TFF1 and TFF3 have markedly different hydrodynamic properties, overall charge, and distribution of surface charge.
May FE, Church ST, Major S, Westley BR. May FE, et al. Biochemistry. 2003 Jul 15;42(27):8250-9. doi: 10.1021/bi030025l. Biochemistry. 2003. PMID: 12846574
Insulin-like growth factors are essential to prevent anoikis in oestrogen-responsive breast cancer cells: importance of the type I IGF receptor and PI3-kinase/Akt pathway.
Luey BC, May FE. Luey BC, et al. Among authors: may fe. Mol Cancer. 2016 Jan 22;15:8. doi: 10.1186/s12943-015-0482-2. Mol Cancer. 2016. PMID: 26801096 Free PMC article.
TFF3 is a valuable predictive biomarker of endocrine response in metastatic breast cancer.
May FE, Westley BR. May FE, et al. Endocr Relat Cancer. 2015 Jun;22(3):465-79. doi: 10.1530/ERC-15-0129. Epub 2015 Apr 21. Endocr Relat Cancer. 2015. PMID: 25900183 Free PMC article.
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