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Hypoxia signalling in cancer and approaches to enforce tumour regression.
Pouysségur J, Dayan F, Mazure NM. Pouysségur J, et al. Among authors: mazure nm. Nature. 2006 May 25;441(7092):437-43. doi: 10.1038/nature04871. Nature. 2006. PMID: 16724055 Review.
Protein kinases and the hypoxia-inducible factor-1, two switches in angiogenesis.
Mazure NM, Brahimi-Horn MC, Pouysségur J. Mazure NM, et al. Curr Pharm Des. 2003;9(7):531-41. doi: 10.2174/1381612033391469. Curr Pharm Des. 2003. PMID: 12570801 Review.
HIF-1: master and commander of the hypoxic world. A pharmacological approach to its regulation by siRNAs.
Mazure NM, Brahimi-Horn MC, Berta MA, Benizri E, Bilton RL, Dayan F, Ginouvès A, Berra E, Pouysségur J. Mazure NM, et al. Biochem Pharmacol. 2004 Sep 15;68(6):971-80. doi: 10.1016/j.bcp.2004.04.022. Biochem Pharmacol. 2004. PMID: 15313390 Review.
Signalling via the hypoxia-inducible factor-1alpha requires multiple posttranslational modifications.
Brahimi-Horn C, Mazure N, Pouysségur J. Brahimi-Horn C, et al. Among authors: mazure n. Cell Signal. 2005 Jan;17(1):1-9. doi: 10.1016/j.cellsig.2004.04.010. Cell Signal. 2005. PMID: 15451019 Review.
Arrest-defective-1 protein, an acetyltransferase, does not alter stability of hypoxia-inducible factor (HIF)-1alpha and is not induced by hypoxia or HIF.
Bilton R, Mazure N, Trottier E, Hattab M, Déry MA, Richard DE, Pouysségur J, Brahimi-Horn MC. Bilton R, et al. Among authors: mazure n. J Biol Chem. 2005 Sep 2;280(35):31132-40. doi: 10.1074/jbc.M504482200. Epub 2005 Jul 1. J Biol Chem. 2005. PMID: 15994306
The oxygen sensor factor-inhibiting hypoxia-inducible factor-1 controls expression of distinct genes through the bifunctional transcriptional character of hypoxia-inducible factor-1alpha.
Dayan F, Roux D, Brahimi-Horn MC, Pouyssegur J, Mazure NM. Dayan F, et al. Among authors: mazure nm. Cancer Res. 2006 Apr 1;66(7):3688-98. doi: 10.1158/0008-5472.CAN-05-4564. Cancer Res. 2006. PMID: 16585195
SUMOylation of hypoxia-inducible factor-1alpha reduces its transcriptional activity.
Berta MA, Mazure N, Hattab M, Pouysségur J, Brahimi-Horn MC. Berta MA, et al. Among authors: mazure n. Biochem Biophys Res Commun. 2007 Aug 31;360(3):646-52. doi: 10.1016/j.bbrc.2007.06.103. Epub 2007 Jun 27. Biochem Biophys Res Commun. 2007. PMID: 17610843
Hypoxia down-regulates CCAAT/enhancer binding protein-alpha expression in breast cancer cells.
Seifeddine R, Dreiem A, Blanc E, Fulchignoni-Lataud MC, Le Frère Belda MA, Lecuru F, Mayi TH, Mazure N, Favaudon V, Massaad C, Barouki R, Massaad-Massade L. Seifeddine R, et al. Among authors: mazure n. Cancer Res. 2008 Apr 1;68(7):2158-65. doi: 10.1158/0008-5472.CAN-07-1190. Cancer Res. 2008. PMID: 18381421
Hif-2alpha mediates UV-induced apoptosis through a novel ATF3-dependent death pathway.
Turchi L, Aberdam E, Mazure N, Pouysségur J, Deckert M, Kitajima S, Aberdam D, Virolle T. Turchi L, et al. Among authors: mazure n. Cell Death Differ. 2008 Sep;15(9):1472-80. doi: 10.1038/cdd.2008.74. Epub 2008 May 30. Cell Death Differ. 2008. PMID: 18511933
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