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85 results

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Page 1
Ras/Raf/MEK/ERK and PI3K/PTEN/Akt/mTOR cascade inhibitors: how mutations can result in therapy resistance and how to overcome resistance.
McCubrey JA, Steelman LS, Chappell WH, Abrams SL, Franklin RA, Montalto G, Cervello M, Libra M, Candido S, Malaponte G, Mazzarino MC, Fagone P, Nicoletti F, Bäsecke J, Mijatovic S, Maksimovic-Ivanic D, Milella M, Tafuri A, Chiarini F, Evangelisti C, Cocco L, Martelli AM. McCubrey JA, et al. Among authors: mazzarino mc. Oncotarget. 2012 Oct;3(10):1068-111. doi: 10.18632/oncotarget.659. Oncotarget. 2012. PMID: 23085539 Free PMC article. Review.
Ras/Raf/MEK/ERK and PI3K/PTEN/Akt/mTOR inhibitors: rationale and importance to inhibiting these pathways in human health.
Chappell WH, Steelman LS, Long JM, Kempf RC, Abrams SL, Franklin RA, Bäsecke J, Stivala F, Donia M, Fagone P, Malaponte G, Mazzarino MC, Nicoletti F, Libra M, Maksimovic-Ivanic D, Mijatovic S, Montalto G, Cervello M, Laidler P, Milella M, Tafuri A, Bonati A, Evangelisti C, Cocco L, Martelli AM, McCubrey JA. Chappell WH, et al. Among authors: mazzarino mc. Oncotarget. 2011 Mar;2(3):135-64. doi: 10.18632/oncotarget.240. Oncotarget. 2011. PMID: 21411864 Free PMC article. Review.
Roles of the Raf/MEK/ERK and PI3K/PTEN/Akt/mTOR pathways in controlling growth and sensitivity to therapy-implications for cancer and aging.
Steelman LS, Chappell WH, Abrams SL, Kempf RC, Long J, Laidler P, Mijatovic S, Maksimovic-Ivanic D, Stivala F, Mazzarino MC, Donia M, Fagone P, Malaponte G, Nicoletti F, Libra M, Milella M, Tafuri A, Bonati A, Bäsecke J, Cocco L, Evangelisti C, Martelli AM, Montalto G, Cervello M, McCubrey JA. Steelman LS, et al. Among authors: mazzarino mc. Aging (Albany NY). 2011 Mar;3(3):192-222. doi: 10.18632/aging.100296. Aging (Albany NY). 2011. PMID: 21422497 Free PMC article. Review.
Mutations and deregulation of Ras/Raf/MEK/ERK and PI3K/PTEN/Akt/mTOR cascades which alter therapy response.
McCubrey JA, Steelman LS, Chappell WH, Abrams SL, Montalto G, Cervello M, Nicoletti F, Fagone P, Malaponte G, Mazzarino MC, Candido S, Libra M, Bäsecke J, Mijatovic S, Maksimovic-Ivanic D, Milella M, Tafuri A, Cocco L, Evangelisti C, Chiarini F, Martelli AM. McCubrey JA, et al. Among authors: mazzarino mc. Oncotarget. 2012 Sep;3(9):954-87. doi: 10.18632/oncotarget.652. Oncotarget. 2012. PMID: 23006971 Free PMC article. Review.
Advances in targeting signal transduction pathways.
McCubrey JA, Steelman LS, Chappell WH, Sun L, Davis NM, Abrams SL, Franklin RA, Cocco L, Evangelisti C, Chiarini F, Martelli AM, Libra M, Candido S, Ligresti G, Malaponte G, Mazzarino MC, Fagone P, Donia M, Nicoletti F, Polesel J, Talamini R, Bäsecke J, Mijatovic S, Maksimovic-Ivanic D, Michele M, Tafuri A, Dulińska-Litewka J, Laidler P, D'Assoro AB, Drobot L, Umezawa D, Montalto G, Cervello M, Demidenko ZN. McCubrey JA, et al. Among authors: mazzarino mc. Oncotarget. 2012 Dec;3(12):1505-21. doi: 10.18632/oncotarget.802. Oncotarget. 2012. PMID: 23455493 Free PMC article. Review.
Detection of BRAF gene mutation in primary choroidal melanoma tissue.
Malaponte G, Libra M, Gangemi P, Bevelacqua V, Mangano K, D'Amico F, Mazzarino MC, Stivala F, McCubrey JA, Travali S. Malaponte G, et al. Among authors: mazzarino mc. Cancer Biol Ther. 2006 Feb;5(2):225-7. doi: 10.4161/cbt.5.2.2429. Epub 2006 Feb 20. Cancer Biol Ther. 2006. PMID: 16410717
Absence of BRAF gene mutation in non-melanoma skin tumors.
Libra M, Malaponte G, Bevelacqua V, Siciliano R, Castrogiovanni P, Fulvi A, Micali G, Ligresti G, Mazzarino MC, Stivala F, Travali S, McCubrey JA. Libra M, et al. Among authors: mazzarino mc. Cell Cycle. 2006 May;5(9):968-70. doi: 10.4161/cc.5.9.2724. Epub 2006 May 1. Cell Cycle. 2006. PMID: 16687919
Analysis of BRAF mutation in primary and metastatic melanoma.
Libra M, Malaponte G, Navolanic PM, Gangemi P, Bevelacqua V, Proietti L, Bruni B, Stivala F, Mazzarino MC, Travali S, McCubrey JA. Libra M, et al. Among authors: mazzarino mc. Cell Cycle. 2005 Oct;4(10):1382-4. doi: 10.4161/cc.4.10.2026. Epub 2005 Oct 13. Cell Cycle. 2005. PMID: 16096377
85 results