Mazzoletti M - Search Results

1

Combined inhibition of Chk1 and Wee1: in vitro synergistic effect translates to tumor growth inhibition in vivo.

Carrassa L, Chilà R, Lupi M, Ricci F, Celenza C, Mazzoletti M, Broggini M, Damia G. Carrassa L, et al. Among authors: mazzoletti m. Cell Cycle. 2012 Jul 1;11(13):2507-17. doi: 10.4161/cc.20899. Epub 2012 Jul 1. Cell Cycle. 2012. PMID: 22713237

2

PI3K/AKT/mTOR inhibitors in ovarian cancer.

Mazzoletti M, Broggini M. Mazzoletti M, et al. Curr Med Chem. 2010;17(36):4433-47. doi: 10.2174/092986710794182999. Curr Med Chem. 2010. PMID: 21062259 Review.

3

Combination of PI3K/mTOR inhibitors: antitumor activity and molecular correlates.

Mazzoletti M, Bortolin F, Brunelli L, Pastorelli R, Di Giandomenico S, Erba E, Ubezio P, Broggini M. Mazzoletti M, et al. Cancer Res. 2011 Jul 1;71(13):4573-84. doi: 10.1158/0008-5472.CAN-10-4322. Epub 2011 May 20. Cancer Res. 2011. PMID: 21602434

4

HtrA2 enhances the apoptotic functions of p73 on bax.

Marabese M, Mazzoletti M, Vikhanskaya F, Broggini M. Marabese M, et al. Among authors: mazzoletti m. Cell Death Differ. 2008 May;15(5):849-58. doi: 10.1038/cdd.2008.7. Epub 2008 Feb 8. Cell Death Differ. 2008. PMID: 18259191

5

Cancer-derived p53 mutants suppress p53-target gene expression--potential mechanism for gain of function of mutant p53.

Vikhanskaya F, Lee MK, Mazzoletti M, Broggini M, Sabapathy K. Vikhanskaya F, et al. Among authors: mazzoletti m. Nucleic Acids Res. 2007;35(6):2093-104. doi: 10.1093/nar/gkm099. Epub 2007 Mar 7. Nucleic Acids Res. 2007. PMID: 17344317 Free PMC article.

6

A novel inhibitor of the PI3K/Akt pathway based on the structure of inositol 1,3,4,5,6-pentakisphosphate.

Falasca M, Chiozzotto D, Godage HY, Mazzoletti M, Riley AM, Previdi S, Potter BV, Broggini M, Maffucci T. Falasca M, et al. Among authors: mazzoletti m. Br J Cancer. 2010 Jan 5;102(1):104-14. doi: 10.1038/sj.bjc.6605408. Br J Cancer. 2010. PMID: 20051961 Free PMC article.

7

Preclinical colorectal cancer chemopreventive efficacy and p53-modulating activity of 3',4',5'-trimethoxyflavonol, a quercetin analogue.

Howells LM, Britton RG, Mazzoletti M, Greaves P, Broggini M, Brown K, Steward WP, Gescher AJ, Sale S. Howells LM, et al. Among authors: mazzoletti m. Cancer Prev Res (Phila). 2010 Aug;3(8):929-39. doi: 10.1158/1940-6207.CAPR-09-0236. Epub 2010 Jul 13. Cancer Prev Res (Phila). 2010. PMID: 20628003 Free PMC article.

8

Phospholipase Cgamma1 is required for metastasis development and progression.

Sala G, Dituri F, Raimondi C, Previdi S, Maffucci T, Mazzoletti M, Rossi C, Iezzi M, Lattanzio R, Piantelli M, Iacobelli S, Broggini M, Falasca M. Sala G, et al. Among authors: mazzoletti m. Cancer Res. 2008 Dec 15;68(24):10187-96. doi: 10.1158/0008-5472.CAN-08-1181. Cancer Res. 2008. PMID: 19074886

9

In vivo target validation by inducible RNAi in human xenograft mouse models.

Mazzoletti M, Texidó G. Mazzoletti M, et al. Methods Mol Biol. 2013;986:325-37. doi: 10.1007/978-1-62703-311-4_20. Methods Mol Biol. 2013. PMID: 23436421

10

Insight into the neuroproteomics effects of the food-contaminant non-dioxin like polychlorinated biphenyls.

Brunelli L, Llansola M, Felipo V, Campagna R, Airoldi L, De Paola M, Fanelli R, Mariani A, Mazzoletti M, Pastorelli R. Brunelli L, et al. Among authors: mazzoletti m. J Proteomics. 2012 Apr 18;75(8):2417-30. doi: 10.1016/j.jprot.2012.02.023. Epub 2012 Feb 24. J Proteomics. 2012. PMID: 22387315

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