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Sperm from mice genetically deficient for the PCSK4 proteinase exhibit accelerated capacitation, precocious acrosome reaction, reduced binding to egg zona pellucida, and impaired fertilizing ability.
Gyamera-Acheampong C, Tantibhedhyangkul J, Weerachatyanukul W, Tadros H, Xu H, van de Loo JW, Pelletier RM, Tanphaichitr N, Mbikay M. Gyamera-Acheampong C, et al. Among authors: mbikay m. Biol Reprod. 2006 Apr;74(4):666-73. doi: 10.1095/biolreprod.105.046821. Epub 2005 Dec 21. Biol Reprod. 2006. PMID: 16371590
116 results