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Overexpression of HSP10 in skeletal muscle of transgenic mice prevents the age-related fall in maximum tetanic force generation and muscle Cross-Sectional Area.
Kayani AC, Close GL, Dillmann WH, Mestril R, Jackson MJ, McArdle A. Kayani AC, et al. Among authors: mcardle a. Am J Physiol Regul Integr Comp Physiol. 2010 Jul;299(1):R268-76. doi: 10.1152/ajpregu.00334.2009. Epub 2010 Apr 21. Am J Physiol Regul Integr Comp Physiol. 2010. PMID: 20410481 Free PMC article.
Long-term administration of the mitochondria-targeted antioxidant mitoquinone mesylate fails to attenuate age-related oxidative damage or rescue the loss of muscle mass and function associated with aging of skeletal muscle.
Sakellariou GK, Pearson T, Lightfoot AP, Nye GA, Wells N, Giakoumaki II, Griffiths RD, McArdle A, Jackson MJ. Sakellariou GK, et al. Among authors: mcardle a. FASEB J. 2016 Nov;30(11):3771-3785. doi: 10.1096/fj.201600450R. Epub 2016 Aug 22. FASEB J. 2016. PMID: 27550965 Free PMC article.
We found that mitoquinone mesylate treatment failed to prevent age-dependent loss of skeletal muscle mass associated with myofiber atrophy or alter a variety of in situ and ex vivo muscle function analyses, including maximum isometric tetanic force, decline in force after …
We found that mitoquinone mesylate treatment failed to prevent age-dependent loss of skeletal muscle mass associated with myofiber atrophy o …
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