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Featured Article: TGF-β1 dominates extracellular matrix rigidity for inducing differentiation of human cardiac fibroblasts to myofibroblasts.
Cho N, Razipour SE, McCain ML. Cho N, et al. Among authors: mccain ml. Exp Biol Med (Maywood). 2018 Apr;243(7):601-612. doi: 10.1177/1535370218761628. Epub 2018 Mar 4. Exp Biol Med (Maywood). 2018. PMID: 29504479 Free PMC article.
Muscle on a chip: in vitro contractility assays for smooth and striated muscle.
Grosberg A, Nesmith AP, Goss JA, Brigham MD, McCain ML, Parker KK. Grosberg A, et al. J Pharmacol Toxicol Methods. 2012 May-Jun;65(3):126-35. doi: 10.1016/j.vascn.2012.04.001. Epub 2012 Apr 12. J Pharmacol Toxicol Methods. 2012. PMID: 22521339 Free PMC article.
Cooperative coupling of cell-matrix and cell-cell adhesions in cardiac muscle.
McCain ML, Lee H, Aratyn-Schaus Y, Kléber AG, Parker KK. McCain ML, et al. Proc Natl Acad Sci U S A. 2012 Jun 19;109(25):9881-6. doi: 10.1073/pnas.1203007109. Epub 2012 Jun 6. Proc Natl Acad Sci U S A. 2012. PMID: 22675119 Free PMC article.
Matrix elasticity regulates the optimal cardiac myocyte shape for contractility.
McCain ML, Yuan H, Pasqualini FS, Campbell PH, Parker KK. McCain ML, et al. Am J Physiol Heart Circ Physiol. 2014 Jun 1;306(11):H1525-39. doi: 10.1152/ajpheart.00799.2013. Epub 2014 Mar 28. Am J Physiol Heart Circ Physiol. 2014. PMID: 24682394 Free PMC article.
Engineering cardiac cell junctions in vitro to study the intercalated disc.
McCain ML, Desplantez T, Kléber AG. McCain ML, et al. Cell Commun Adhes. 2014 Jun;21(3):181-91. doi: 10.3109/15419061.2014.905931. Epub 2014 Apr 23. Cell Commun Adhes. 2014. PMID: 24754499 Review.
Cytoskeletal prestress regulates nuclear shape and stiffness in cardiac myocytes.
Lee H, Adams WJ, Alford PW, McCain ML, Feinberg AW, Sheehy SP, Goss JA, Parker KK. Lee H, et al. Exp Biol Med (Maywood). 2015 Nov;240(11):1543-54. doi: 10.1177/1535370215583799. Epub 2015 Apr 23. Exp Biol Med (Maywood). 2015. PMID: 25908635 Free PMC article.
Prolonged Culture of Aligned Skeletal Myotubes on Micromolded Gelatin Hydrogels.
Bettadapur A, Suh GC, Geisse NA, Wang ER, Hua C, Huber HA, Viscio AA, Kim JY, Strickland JB, McCain ML. Bettadapur A, et al. Sci Rep. 2016 Jun 28;6:28855. doi: 10.1038/srep28855. Sci Rep. 2016. PMID: 27350122 Free PMC article.
Toward improved myocardial maturity in an organ-on-chip platform with immature cardiac myocytes.
Sheehy SP, Grosberg A, Qin P, Behm DJ, Ferrier JP, Eagleson MA, Nesmith AP, Krull D, Falls JG, Campbell PH, McCain ML, Willette RN, Hu E, Parker KK. Sheehy SP, et al. Exp Biol Med (Maywood). 2017 Nov;242(17):1643-1656. doi: 10.1177/1535370217701006. Epub 2017 Mar 26. Exp Biol Med (Maywood). 2017. PMID: 28343439 Free PMC article.
Engineering micromyocardium to delineate cellular and extracellular regulation of myocardial tissue contractility.
Ariyasinghe NR, Reck CH, Viscio AA, Petersen AP, Lyra-Leite DM, Cho N, McCain ML. Ariyasinghe NR, et al. Integr Biol (Camb). 2017 Sep 18;9(9):730-741. doi: 10.1039/c7ib00081b. Integr Biol (Camb). 2017. PMID: 28726917
Mitochondrial function in engineered cardiac tissues is regulated by extracellular matrix elasticity and tissue alignment.
Lyra-Leite DM, Andres AM, Petersen AP, Ariyasinghe NR, Cho N, Lee JA, Gottlieb RA, McCain ML. Lyra-Leite DM, et al. Am J Physiol Heart Circ Physiol. 2017 Oct 1;313(4):H757-H767. doi: 10.1152/ajpheart.00290.2017. Epub 2017 Jul 21. Am J Physiol Heart Circ Physiol. 2017. PMID: 28733449 Free PMC article.
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