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Merlin and ERM proteins: unappreciated roles in cancer development?
McClatchey AI. McClatchey AI. Nat Rev Cancer. 2003 Nov;3(11):877-83. doi: 10.1038/nrc1213. Nat Rev Cancer. 2003. PMID: 14668818 Review. No abstract available.
Mice heterozygous for a mutation at the Nf2 tumor suppressor locus develop a range of highly metastatic tumors.
McClatchey AI, Saotome I, Mercer K, Crowley D, Gusella JF, Bronson RT, Jacks T. McClatchey AI, et al. Genes Dev. 1998 Apr 15;12(8):1121-33. doi: 10.1101/gad.12.8.1121. Genes Dev. 1998. PMID: 9553042 Free PMC article.
Modeling metastasis in the mouse.
McClatchey AI. McClatchey AI. Oncogene. 1999 Sep 20;18(38):5334-9. doi: 10.1038/sj.onc.1203086. Oncogene. 1999. PMID: 10498886 Review. No abstract available.
Mouse models of neurofibromatosis.
McClatchey AI, Cichowski K. McClatchey AI, et al. Biochim Biophys Acta. 2001;1471(2):M73-80. doi: 10.1016/s0304-419x(00)00026-3. Biochim Biophys Acta. 2001. PMID: 11342186 Review. No abstract available.
The Nf2 tumor suppressor, merlin, functions in Rac-dependent signaling.
Shaw RJ, Paez JG, Curto M, Yaktine A, Pruitt WM, Saotome I, O'Bryan JP, Gupta V, Ratner N, Der CJ, Jacks T, McClatchey AI. Shaw RJ, et al. Dev Cell. 2001 Jul;1(1):63-72. doi: 10.1016/s1534-5807(01)00009-0. Dev Cell. 2001. PMID: 11703924
DOCK4, a GTPase activator, is disrupted during tumorigenesis.
Yajnik V, Paulding C, Sordella R, McClatchey AI, Saito M, Wahrer DC, Reynolds P, Bell DW, Lake R, van den Heuvel S, Settleman J, Haber DA. Yajnik V, et al. Cell. 2003 Mar 7;112(5):673-84. doi: 10.1016/s0092-8674(03)00155-7. Cell. 2003. PMID: 12628187
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