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Nf2/Merlin: a coordinator of receptor signalling and intercellular contact.
Curto M, McClatchey AI. Curto M, et al. Br J Cancer. 2008 Jan 29;98(2):256-62. doi: 10.1038/sj.bjc.6604002. Epub 2007 Oct 30. Br J Cancer. 2008. PMID: 17971776 Free PMC article. Review.
Mice heterozygous for a mutation at the Nf2 tumor suppressor locus develop a range of highly metastatic tumors.
McClatchey AI, Saotome I, Mercer K, Crowley D, Gusella JF, Bronson RT, Jacks T. McClatchey AI, et al. Genes Dev. 1998 Apr 15;12(8):1121-33. doi: 10.1101/gad.12.8.1121. Genes Dev. 1998. PMID: 9553042 Free PMC article.
Modeling metastasis in the mouse.
McClatchey AI. McClatchey AI. Oncogene. 1999 Sep 20;18(38):5334-9. doi: 10.1038/sj.onc.1203086. Oncogene. 1999. PMID: 10498886 Review. No abstract available.
Mouse models of neurofibromatosis.
McClatchey AI, Cichowski K. McClatchey AI, et al. Biochim Biophys Acta. 2001;1471(2):M73-80. doi: 10.1016/s0304-419x(00)00026-3. Biochim Biophys Acta. 2001. PMID: 11342186 Review. No abstract available.
The Nf2 tumor suppressor, merlin, functions in Rac-dependent signaling.
Shaw RJ, Paez JG, Curto M, Yaktine A, Pruitt WM, Saotome I, O'Bryan JP, Gupta V, Ratner N, Der CJ, Jacks T, McClatchey AI. Shaw RJ, et al. Dev Cell. 2001 Jul;1(1):63-72. doi: 10.1016/s1534-5807(01)00009-0. Dev Cell. 2001. PMID: 11703924
NF2 deficiency promotes tumorigenesis and metastasis by destabilizing adherens junctions.
Lallemand D, Curto M, Saotome I, Giovannini M, McClatchey AI. Lallemand D, et al. Genes Dev. 2003 May 1;17(9):1090-100. doi: 10.1101/gad.1054603. Epub 2003 Apr 14. Genes Dev. 2003. PMID: 12695331 Free PMC article.
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