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Tumour necrosis factor alpha (TNF-alpha) interferes with Fas-mediated apoptotic cell death on rheumatoid arthritis (RA) synovial cells: a possible mechanism of rheumatoid synovial hyperplasia and a clinical benefit of anti-TNF-alpha therapy for RA.
Ohshima S, Mima T, Sasai M, Nishioka K, Shimizu M, Murata N, Yoshikawa H, Nakanishi K, Suemura M, McCloskey RV, Kishimoto T, Saeki Y. Ohshima S, et al. Among authors: mccloskey rv. Cytokine. 2000 Mar;12(3):281-8. doi: 10.1006/cyto.1999.0552. Cytokine. 2000. PMID: 10704256
Long-term follow-up of the changes in circulating cytokines, soluble cytokine receptors, and white blood cell subset counts in patients with rheumatoid arthritis (RA) after monoclonal anti-TNF alpha antibody therapy.
Ohshima S, Saeki Y, Mima T, Sasai M, Nishioka K, Ishida H, Shimizu M, Suemura M, McCloskey R, Kishimoto T. Ohshima S, et al. Among authors: mccloskey r. J Clin Immunol. 1999 Sep;19(5):305-13. doi: 10.1023/a:1020543625282. J Clin Immunol. 1999. PMID: 10535607 Clinical Trial.
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