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Excess of metalloproteases over tissue inhibitor of metalloprotease may contribute to cartilage degradation in osteoarthritis and rheumatoid arthritis.
Martel-Pelletier J, McCollum R, Fujimoto N, Obata K, Cloutier JM, Pelletier JP. Martel-Pelletier J, et al. Among authors: mccollum r. Lab Invest. 1994 Jun;70(6):807-15. Lab Invest. 1994. PMID: 8015285
The synthesis of IL-1 receptor antagonist (IL-1ra) by synovial fibroblasts is markedly increased by the cytokines TNF-alpha and IL-1.
Martel-Pelletier J, McCollum R, Pelletier JP. Martel-Pelletier J, et al. Among authors: mccollum r. Biochim Biophys Acta. 1993 Feb 17;1175(3):302-5. doi: 10.1016/0167-4889(93)90221-a. Biochim Biophys Acta. 1993. PMID: 8435447
Regulation of human normal and osteoarthritic chondrocyte interleukin-1 receptor by antirheumatic drugs.
Pelletier JP, McCollum R, DiBattista J, Loose LD, Cloutier JM, Martel-Pelletier J. Pelletier JP, et al. Among authors: mccollum r. Arthritis Rheum. 1993 Nov;36(11):1517-27. doi: 10.1002/art.1780361106. Arthritis Rheum. 1993. PMID: 8240429
Cytokines and inflammation in cartilage degradation.
Pelletier JP, DiBattista JA, Roughley P, McCollum R, Martel-Pelletier J. Pelletier JP, et al. Among authors: mccollum r. Rheum Dis Clin North Am. 1993 Aug;19(3):545-68. Rheum Dis Clin North Am. 1993. PMID: 8210574 Review.
Synthesis of metalloproteases and interleukin 6 (IL-6) in human osteoarthritic synovial membrane is an IL-1 mediated process.
Pelletier JP, McCollum R, Cloutier JM, Martel-Pelletier J. Pelletier JP, et al. Among authors: mccollum r. J Rheumatol Suppl. 1995 Feb;43:109-14. J Rheumatol Suppl. 1995. PMID: 7752112
Are cytokines involved in osteoarthritic pathophysiology?
Pelletier JP, Roughley PJ, DiBattista JA, McCollum R, Martel-Pelletier J. Pelletier JP, et al. Among authors: mccollum r. Semin Arthritis Rheum. 1991 Jun;20(6 Suppl 2):12-25. doi: 10.1016/0049-0172(91)90024-t. Semin Arthritis Rheum. 1991. PMID: 1866626 Review.
Regulation of interleukin 1 receptors in human articular chondrocytes.
McCollum R, Martel-Pelletier J, DiBattista J, Pelletier JP. McCollum R, et al. J Rheumatol Suppl. 1991 Feb;27:85-8. J Rheumatol Suppl. 1991. PMID: 1827502
Plasmin, plasminogen activators and inhibitor in human osteoarthritic cartilage.
Martel-Pelletier J, Faure MP, McCollum R, Mineau F, Cloutier JM, Pelletier JP. Martel-Pelletier J, et al. Among authors: mccollum r. J Rheumatol. 1991 Dec;18(12):1863-71. J Rheumatol. 1991. PMID: 1724464
The interleukin-1 receptor in normal and osteoarthritic human articular chondrocytes. Identification as the type I receptor and analysis of binding kinetics and biologic function.
Martel-Pelletier J, McCollum R, DiBattista J, Faure MP, Chin JA, Fournier S, Sarfati M, Pelletier JP. Martel-Pelletier J, et al. Among authors: mccollum r. Arthritis Rheum. 1992 May;35(5):530-40. doi: 10.1002/art.1780350507. Arthritis Rheum. 1992. PMID: 1533521
Effects of tiaprofenic acid on plasminogen activators and inhibitors in human OA and RA synovium.
Pelletier JP, McCollum R, Cloutier JM, Martel-Pelletier J. Pelletier JP, et al. Among authors: mccollum r. Br J Rheumatol. 1992;31 Suppl 1:19-26. Br J Rheumatol. 1992. PMID: 1555050
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