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Common and rare variant association analyses in amyotrophic lateral sclerosis identify 15 risk loci with distinct genetic architectures and neuron-specific biology.
van Rheenen W, van der Spek RAA, Bakker MK, van Vugt JJFA, Hop PJ, Zwamborn RAJ, de Klein N, Westra HJ, Bakker OB, Deelen P, Shireby G, Hannon E, Moisse M, Baird D, Restuadi R, Dolzhenko E, Dekker AM, Gawor K, Westeneng HJ, Tazelaar GHP, van Eijk KR, Kooyman M, Byrne RP, Doherty M, Heverin M, Al Khleifat A, Iacoangeli A, Shatunov A, Ticozzi N, Cooper-Knock J, Smith BN, Gromicho M, Chandran S, Pal S, Morrison KE, Shaw PJ, Hardy J, Orrell RW, Sendtner M, Meyer T, Başak N, van der Kooi AJ, Ratti A, Fogh I, Gellera C, Lauria G, Corti S, Cereda C, Sproviero D, D'Alfonso S, Sorarù G, Siciliano G, Filosto M, Padovani A, Chiò A, Calvo A, Moglia C, Brunetti M, Canosa A, Grassano M, Beghi E, Pupillo E, Logroscino G, Nefussy B, Osmanovic A, Nordin A, Lerner Y, Zabari M, Gotkine M, Baloh RH, Bell S, Vourc'h P, Corcia P, Couratier P, Millecamps S, Meininger V, Salachas F, Mora Pardina JS, Assialioui A, Rojas-García R, Dion PA, Ross JP, Ludolph AC, Weishaupt JH, Brenner D, Freischmidt A, Bensimon G, Brice A, Durr A, Payan CAM, Saker-Delye S, Wood NW, Topp S, Rademakers R, Tittmann L, Lieb W, Franke A, Ripke S, Braun A, Kraft J, Whiteman DC, Olsen CM, Uitterlinden AG, Hofman A, Rietschel M, Cich… See abstract for full author list ➔ van Rheenen W, et al. Among authors: mccombe pa. Nat Genet. 2021 Dec;53(12):1636-1648. doi: 10.1038/s41588-021-00973-1. Epub 2021 Dec 6. Nat Genet. 2021. PMID: 34873335 Free PMC article.
Motor unit number estimation--a Bayesian approach.
Ridall PG, Pettitt AN, Henderson RD, McCombe PA. Ridall PG, et al. Among authors: mccombe pa. Biometrics. 2006 Dec;62(4):1235-50. doi: 10.1111/j.1541-0420.2006.00577.x. Biometrics. 2006. PMID: 17156299
Bayesian statistical MUNE method.
Henderson RD, Ridall PG, Hutchinson NM, Pettitt AN, McCombe PA. Henderson RD, et al. Among authors: mccombe pa. Muscle Nerve. 2007 Aug;36(2):206-13. doi: 10.1002/mus.20805. Muscle Nerve. 2007. PMID: 17487869
Immune activation in the peripheral blood of patients with acute ischemic stroke.
Yan J, Greer JM, Etherington K, Cadigan GP, Cavanagh H, Henderson RD, O'Sullivan JD, Pandian JD, Read SJ, McCombe PA. Yan J, et al. Among authors: mccombe pa. J Neuroimmunol. 2009 Jan 3;206(1-2):112-7. doi: 10.1016/j.jneuroim.2008.11.001. Epub 2008 Dec 5. J Neuroimmunol. 2009. PMID: 19058859
CMAP decrement in ALS.
Henderson R, Baumann F, Hutchinson N, McCombe P. Henderson R, et al. Muscle Nerve. 2009 Apr;39(4):555-6. doi: 10.1002/mus.21105. Muscle Nerve. 2009. PMID: 19296459 No abstract available.
263 results