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Therapeutic strategies for targeting ras proteins.
Gysin S, Salt M, Young A, McCormick F. Gysin S, et al. Among authors: mccormick f. Genes Cancer. 2011 Mar;2(3):359-72. doi: 10.1177/1947601911412376. Genes Cancer. 2011. PMID: 21779505 Free PMC article.
Mutational activation of RAS and GSP oncogenes in differentiated thyroid cancer and their biological implications.
Goretzki PE, Lyons J, Stacy-Phipps S, Rosenau W, Demeure M, Clark OH, McCormick F, Röher HD, Bourne HR. Goretzki PE, et al. Among authors: mccormick f. World J Surg. 1992 Jul-Aug;16(4):576-81; discussion 581-2. doi: 10.1007/BF02067325. World J Surg. 1992. PMID: 1413827
Human bladder and colon carcinomas contain activated ras p21. Specific detection of twelfth codon mutants.
Meyers FJ, Gumerlock PH, Kokoris SP, deVere White RW, McCormick F. Meyers FJ, et al. Among authors: mccormick f. Cancer. 1989 Jun 1;63(11):2177-81. doi: 10.1002/1097-0142(19890601)63:11<2177::aid-cncr2820631119>3.0.co;2-v. Cancer. 1989. PMID: 2655864
Activators and effectors of ras p21 proteins.
McCormick F. McCormick F. Curr Opin Genet Dev. 1994 Feb;4(1):71-6. doi: 10.1016/0959-437x(94)90093-0. Curr Opin Genet Dev. 1994. PMID: 8193543 Review.
Ras-related proteins in signal transduction and growth control.
McCormick F. McCormick F. Mol Reprod Dev. 1995 Dec;42(4):500-6. doi: 10.1002/mrd.1080420419. Mol Reprod Dev. 1995. PMID: 8607982 Review.
This cascade is controlled at several points: Ras p21 proteins are regulated by GAPs and by exchange factors, whose activities are altered by growth factor receptor activation (Boguski and McCormick, 1993: Nature 366:643-654). ...
This cascade is controlled at several points: Ras p21 proteins are regulated by GAPs and by exchange factors, whose activities are altered b …
The superfamily of Ras-related GTPases.
McCormick F. McCormick F. Jpn J Cancer Res. 1997 Jul;88(7):inside front cover. Jpn J Cancer Res. 1997. PMID: 9310130 No abstract available.
Beta-catenin regulates expression of cyclin D1 in colon carcinoma cells.
Tetsu O, McCormick F. Tetsu O, et al. Among authors: mccormick f. Nature. 1999 Apr 1;398(6726):422-6. doi: 10.1038/18884. Nature. 1999. PMID: 10201372
Cancer therapy based on p53.
McCormick F. McCormick F. Cancer J Sci Am. 1999 May-Jun;5(3):139-44. Cancer J Sci Am. 1999. PMID: 10367167 Review. No abstract available.
Wnt signaling to beta-catenin involves two interactive components. Glycogen synthase kinase-3beta inhibition and activation of protein kinase C.
Chen RH, Ding WV, McCormick F. Chen RH, et al. Among authors: mccormick f. J Biol Chem. 2000 Jun 9;275(23):17894-9. doi: 10.1074/jbc.M905336199. J Biol Chem. 2000. PMID: 10749878
Opposing effects of Ras on p53: transcriptional activation of mdm2 and induction of p19ARF.
Ries S, Biederer C, Woods D, Shifman O, Shirasawa S, Sasazuki T, McMahon M, Oren M, McCormick F. Ries S, et al. Among authors: mccormick f. Cell. 2000 Oct 13;103(2):321-30. doi: 10.1016/s0092-8674(00)00123-9. Cell. 2000. PMID: 11057904
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