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Prospective antiretroviral treatment of asymptomatic, HIV-1 infected controllers.
Hatano H, Yukl SA, Ferre AL, Graf EH, Somsouk M, Sinclair E, Abdel-Mohsen M, Liegler T, Harvill K, Hoh R, Palmer S, Bacchetti P, Hunt PW, Martin JN, McCune JM, Tracy RP, Busch MP, O'Doherty U, Shacklett BL, Wong JK, Deeks SG. Hatano H, et al. Among authors: mccune jm. PLoS Pathog. 2013;9(10):e1003691. doi: 10.1371/journal.ppat.1003691. Epub 2013 Oct 10. PLoS Pathog. 2013. PMID: 24130489 Free PMC article. Clinical Trial.
Immunosenescence and HIV.
Deeks SG, Verdin E, McCune JM. Deeks SG, et al. Among authors: mccune jm. Curr Opin Immunol. 2012 Aug;24(4):501-6. doi: 10.1016/j.coi.2012.05.004. Epub 2012 Jun 2. Curr Opin Immunol. 2012. PMID: 22658763 Review.
Antiretroviral therapy initiated within 6 months of HIV infection is associated with lower T-cell activation and smaller HIV reservoir size.
Jain V, Hartogensis W, Bacchetti P, Hunt PW, Hatano H, Sinclair E, Epling L, Lee TH, Busch MP, McCune JM, Pilcher CD, Hecht FM, Deeks SG. Jain V, et al. Among authors: mccune jm. J Infect Dis. 2013 Oct 15;208(8):1202-11. doi: 10.1093/infdis/jit311. Epub 2013 Jul 12. J Infect Dis. 2013. PMID: 23852127 Free PMC article.
Discordance between peripheral and colonic markers of inflammation during suppressive ART.
Dunham RM, Vujkovic-Cvijin I, Yukl SA, Broadhurst MJ, Loke P, Albright RG, Wong JK, Lederman MM, Somsouk M, Hunt PW, Martin JN, Deeks SG, McCune JM. Dunham RM, et al. Among authors: mccune jm. J Acquir Immune Defic Syndr. 2014 Feb 1;65(2):133-41. doi: 10.1097/01.qai.0000437172.08127.0b. J Acquir Immune Defic Syndr. 2014. PMID: 24121758 Free PMC article.
HIV-infected individuals with low CD4/CD8 ratio despite effective antiretroviral therapy exhibit altered T cell subsets, heightened CD8+ T cell activation, and increased risk of non-AIDS morbidity and mortality.
Serrano-Villar S, Sainz T, Lee SA, Hunt PW, Sinclair E, Shacklett BL, Ferre AL, Hayes TL, Somsouk M, Hsue PY, Van Natta ML, Meinert CL, Lederman MM, Hatano H, Jain V, Huang Y, Hecht FM, Martin JN, McCune JM, Moreno S, Deeks SG. Serrano-Villar S, et al. Among authors: mccune jm. PLoS Pathog. 2014 May 15;10(5):e1004078. doi: 10.1371/journal.ppat.1004078. eCollection 2014 May. PLoS Pathog. 2014. PMID: 24831517 Free PMC article. Clinical Trial.
263 results