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A selective BCL-XL PROTAC degrader achieves safe and potent antitumor activity.
Khan S, Zhang X, Lv D, Zhang Q, He Y, Zhang P, Liu X, Thummuri D, Yuan Y, Wiegand JS, Pei J, Zhang W, Sharma A, McCurdy CR, Kuruvilla VM, Baran N, Ferrando AA, Kim YM, Rogojina A, Houghton PJ, Huang G, Hromas R, Konopleva M, Zheng G, Zhou D. Khan S, et al. Among authors: mccurdy cr. Nat Med. 2019 Dec;25(12):1938-1947. doi: 10.1038/s41591-019-0668-z. Epub 2019 Dec 2. Nat Med. 2019. PMID: 31792461 Free PMC article.
Evaluation of the rewarding effects of mitragynine and 7-hydroxymitragynine in an intracranial self-stimulation procedure in male and female rats.
Behnood-Rod A, Chellian R, Wilson R, Hiranita T, Sharma A, Leon F, McCurdy CR, McMahon LR, Bruijnzeel AW. Behnood-Rod A, et al. Among authors: mccurdy cr. Drug Alcohol Depend. 2020 Oct 1;215:108235. doi: 10.1016/j.drugalcdep.2020.108235. Epub 2020 Aug 18. Drug Alcohol Depend. 2020. PMID: 32889450 Free PMC article.
UPLC-MS/MS method for the quantification of MCI-77, a novel sigma-1 receptor ligand, and its application to pharmacokinetic studies.
Popa R, Kamble SH, Kanumuri RS, King TI, Berthold EC, Intagliata S, Sharma A, McCurdy CR. Popa R, et al. Among authors: mccurdy cr. J Chromatogr B Analyt Technol Biomed Life Sci. 2022 Apr 30;1196:123187. doi: 10.1016/j.jchromb.2022.123187. Epub 2022 Mar 5. J Chromatogr B Analyt Technol Biomed Life Sci. 2022. PMID: 35278810 Free PMC article.
190 results