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The production of hydrogen sulfide limits myocardial ischemia and reperfusion injury and contributes to the cardioprotective effects of preconditioning with endotoxin, but not ischemia in the rat.
Sivarajah A, McDonald MC, Thiemermann C. Sivarajah A, et al. Among authors: mcdonald mc. Shock. 2006 Aug;26(2):154-61. doi: 10.1097/01.shk.0000225722.56681.64. Shock. 2006. PMID: 16878023
Tyrphostin reduces the organ injury in haemorrhagic shock: role of inducible nitric oxide synthase.
McDonald M, Abdelrahman M, Cuzzocrea S, Thiemermann C. McDonald M, et al. Resuscitation. 2003 Sep;58(3):349-61. doi: 10.1016/s0300-9572(03)00156-4. Resuscitation. 2003. PMID: 12969613
Peptidoglycan and lipoteichoic acid in gram-positive bacterial sepsis: receptors, signal transduction, biological effects, and synergism.
Wang JE, Dahle MK, McDonald M, Foster SJ, Aasen AO, Thiemermann C. Wang JE, et al. Among authors: mcdonald m. Shock. 2003 Nov;20(5):402-14. doi: 10.1097/01.shk.0000092268.01859.0d. Shock. 2003. PMID: 14560103 Review.
A novel, potent and selective inhibitor of the activity of inducible nitric oxide synthase (GW274150) reduces the organ injury in hemorrhagic shock.
McDonald MC, Izumi M, Cuzzocrea S, Thiemermann C. McDonald MC, et al. J Physiol Pharmacol. 2002 Dec;53(4 Pt 1):555-69. J Physiol Pharmacol. 2002. PMID: 12512692
5-aminoisoquinolinone, a potent inhibitor of poly (adenosine 5'-diphosphate ribose) polymerase, reduces myocardial infarct size.
Wayman N, McDonald MC, Thompson AS, Threadgill MD, Thiemermann C. Wayman N, et al. Among authors: mcdonald mc. Eur J Pharmacol. 2001 Oct 26;430(1):93-100. doi: 10.1016/s0014-2999(01)01359-0. Eur J Pharmacol. 2001. PMID: 11698068
High density lipoproteins reduce organ injury and organ dysfunction in a rat model of hemorrhagic shock.
Cockerill GW, McDonald MC, Mota-Filipe H, Cuzzocrea S, Miller NE, Thiemermann C. Cockerill GW, et al. Among authors: mcdonald mc. FASEB J. 2001 Sep;15(11):1941-52. doi: 10.1096/fj.01-0075com. FASEB J. 2001. PMID: 11532974
Calpain inhibitor-1 reduces renal ischemia/reperfusion injury in the rat.
Chatterjee PK, Brown PA, Cuzzocrea S, Zacharowski K, Stewart KN, Mota-Filipe H, McDonald MC, Thiemermann C. Chatterjee PK, et al. Among authors: mcdonald mc. Kidney Int. 2001 Jun;59(6):2073-83. doi: 10.1046/j.1523-1755.2001.00722.x. Kidney Int. 2001. PMID: 11380809
Calpain inhibitor I reduces the activation of nuclear factor-kappaB and organ injury/dysfunction in hemorrhagic shock.
McDonald MC, Mota-Filipe H, Paul A, Cuzzocrea S, Abdelrahman M, Harwood S, Plevin R, Chatterjee PK, Yaqoob MM, Thiemermann C. McDonald MC, et al. FASEB J. 2001 Jan;15(1):171-186. doi: 10.1096/fj.99-0645com. FASEB J. 2001. PMID: 11149905
Effects of 5-aminoisoquinolinone, a water-soluble, potent inhibitor of the activity of poly (ADP-ribose) polymerase on the organ injury and dysfunction caused by haemorrhagic shock.
McDonald MC, Mota-Filipe H, Wright JA, Abdelrahman M, Threadgill MD, Thompson AS, Thiemermann C. McDonald MC, et al. Br J Pharmacol. 2000 Jun;130(4):843-50. doi: 10.1038/sj.bjp.0703391. Br J Pharmacol. 2000. PMID: 10864891 Free PMC article.
Effects of inhibitors of the activity of poly (ADP-ribose) synthetase on the organ injury and dysfunction caused by haemorrhagic shock.
McDonald MC, Filipe HM, Thiemermann C. McDonald MC, et al. Br J Pharmacol. 1999 Nov;128(6):1339-45. doi: 10.1038/sj.bjp.0702928. Br J Pharmacol. 1999. PMID: 10578150 Free PMC article.
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