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Assessing the contribution of rare variants to complex trait heritability from whole-genome sequence data.
Wainschtein P, Jain D, Zheng Z; TOPMed Anthropometry Working Group; NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium; Cupples LA, Shadyab AH, McKnight B, Shoemaker BM, Mitchell BD, Psaty BM, Kooperberg C, Liu CT, Albert CM, Roden D, Chasman DI, Darbar D, Lloyd-Jones DM, Arnett DK, Regan EA, Boerwinkle E, Rotter JI, O'Connell JR, Yanek LR, de Andrade M, Allison MA, McDonald MN, Chung MK, Fornage M, Chami N, Smith NL, Ellinor PT, Vasan RS, Mathias RA, Loos RJF, Rich SS, Lubitz SA, Heckbert SR, Redline S, Guo X, Chen Y-I, Laurie CA, Hernandez RD, McGarvey ST, Goddard ME, Laurie CC, North KE, Lange LA, Weir BS, Yengo L, Yang J, Visscher PM. Wainschtein P, et al. Among authors: mcdonald mn. Nat Genet. 2022 Mar;54(3):263-273. doi: 10.1038/s41588-021-00997-7. Epub 2022 Mar 7. Nat Genet. 2022. PMID: 35256806 Free PMC article.
Susceptibility to Childhood Pneumonia: A Genome-Wide Analysis.
Hayden LP, Cho MH, McDonald MN, Crapo JD, Beaty TH, Silverman EK, Hersh CP; COPDGene Investigators *. Hayden LP, et al. Among authors: mcdonald mn. Am J Respir Cell Mol Biol. 2017 Jan;56(1):20-28. doi: 10.1165/rcmb.2016-0101OC. Am J Respir Cell Mol Biol. 2017. PMID: 27508494 Free PMC article. Clinical Trial.
Clinical, physiologic, and radiographic factors contributing to development of hypoxemia in moderate to severe COPD: a cohort study.
Wells JM, Estepar RS, McDonald MN, Bhatt SP, Diaz AA, Bailey WC, Jacobson FL, Dransfield MT, Washko GR, Make BJ, Casaburi R, van Beek EJ, Hoffman EA, Sciurba FC, Crapo JD, Silverman EK, Hersh CP; COPDGene Investigators. Wells JM, et al. Among authors: mcdonald mn. BMC Pulm Med. 2016 Dec 1;16(1):169. doi: 10.1186/s12890-016-0331-0. BMC Pulm Med. 2016. PMID: 27903260 Free PMC article.
Body mass index change in gastrointestinal cancer and chronic obstructive pulmonary disease is associated with Dedicator of Cytokinesis 1.
McDonald MN, Won S, Mattheisen M, Castaldi PJ, Cho MH, Rutten E, Hardin M, Yip WK, Rennard SI, Lomas DA, Wouters EFM, Agusti A, Casaburi R, Lange CP, O'Connor G, Hersh CP, Silverman EK. McDonald MN, et al. J Cachexia Sarcopenia Muscle. 2017 Jun;8(3):428-436. doi: 10.1002/jcsm.12171. Epub 2017 Jan 2. J Cachexia Sarcopenia Muscle. 2017. PMID: 28044437 Free PMC article.
Handgrip Strength in Chronic Obstructive Pulmonary Disease. Associations with Acute Exacerbations and Body Composition.
Martinez CH, Diaz AA, Meldrum CA, McDonald MN, Murray S, Kinney GL, Hokanson JE, Curtis JL, Bowler RP, Han MK, Washko GR, Regan EA; COPDGene Investigators. Martinez CH, et al. Among authors: mcdonald mn. Ann Am Thorac Soc. 2017 Nov;14(11):1638-1645. doi: 10.1513/AnnalsATS.201610-821OC. Ann Am Thorac Soc. 2017. PMID: 29090990 Free PMC article.
Chest computed tomography-derived low fat-free mass index and mortality in COPD.
McDonald MN, Diaz AA, Rutten E, Lutz SM, Harmouche R, San Jose Estepar R, Kinney G, Hokanson JE, Gower BA, Wouters EFM, Rennard SI, Hersh CP, Casaburi R, Dransfield MT, Silverman EK, Washko GR. McDonald MN, et al. Eur Respir J. 2017 Dec 14;50(6):1701134. doi: 10.1183/13993003.01134-2017. Print 2017 Dec. Eur Respir J. 2017. PMID: 29242259 Free PMC article.
Common and Rare Variants Genetic Association Analysis of Cigarettes per Day Among Ever-Smokers in Chronic Obstructive Pulmonary Disease Cases and Controls.
Lutz SM, Frederiksen B, Begum F, McDonald MN, Cho MH, Hobbs BD, Parker MM, DeMeo DL, Hersh CP, Ehringer MA, Young K, Jiang L, Foreman MG, Kinney GL, Make BJ, Lomas DA, Bakke P, Gulsvik A, Crapo JD, Silverman EK, Beaty TH, Hokanson JE; ECLIPSE and COPDGene Investigators. Lutz SM, et al. Among authors: mcdonald mn. Nicotine Tob Res. 2019 May 21;21(6):714-722. doi: 10.1093/ntr/nty095. Nicotine Tob Res. 2019. PMID: 29767774 Free PMC article.
Whole-Genome Sequencing in Severe Chronic Obstructive Pulmonary Disease.
Prokopenko D, Sakornsakolpat P, Fier HL, Qiao D, Parker MM, McDonald MN, Manichaikul A, Rich SS, Barr RG, Williams CJ, Brantly ML, Lange C, Beaty TH, Crapo JD, Silverman EK, Cho MH. Prokopenko D, et al. Among authors: mcdonald mn. Am J Respir Cell Mol Biol. 2018 Nov;59(5):614-622. doi: 10.1165/rcmb.2018-0088OC. Am J Respir Cell Mol Biol. 2018. PMID: 29949718 Free PMC article.
37 results