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Exploiting structural principles to design cyclin-dependent kinase inhibitors.
Noble M, Barrett P, Endicott J, Johnson L, McDonnell J, Robertson G, Zawaira A. Noble M, et al. Among authors: mcdonnell j. Biochim Biophys Acta. 2005 Dec 30;1754(1-2):58-64. doi: 10.1016/j.bbapap.2005.08.019. Epub 2005 Sep 12. Biochim Biophys Acta. 2005. PMID: 16361058 Review.
Isoindolinone inhibitors of the murine double minute 2 (MDM2)-p53 protein-protein interaction: structure-activity studies leading to improved potency.
Hardcastle IR, Liu J, Valeur E, Watson A, Ahmed SU, Blackburn TJ, Bennaceur K, Clegg W, Drummond C, Endicott JA, Golding BT, Griffin RJ, Gruber J, Haggerty K, Harrington RW, Hutton C, Kemp S, Lu X, McDonnell JM, Newell DR, Noble ME, Payne SL, Revill CH, Riedinger C, Xu Q, Lunec J. Hardcastle IR, et al. Among authors: mcdonnell jm. J Med Chem. 2011 Mar 10;54(5):1233-43. doi: 10.1021/jm1011929. Epub 2011 Feb 11. J Med Chem. 2011. PMID: 21314128
MDM2-p53 protein-protein interaction inhibitors: a-ring substituted isoindolinones.
Watson AF, Liu J, Bennaceur K, Drummond CJ, Endicott JA, Golding BT, Griffin RJ, Haggerty K, Lu X, McDonnell JM, Newell DR, Noble ME, Revill CH, Riedinger C, Xu Q, Zhao Y, Lunec J, Hardcastle IR. Watson AF, et al. Among authors: mcdonnell jm. Bioorg Med Chem Lett. 2011 Oct 1;21(19):5916-9. doi: 10.1016/j.bmcl.2011.07.084. Epub 2011 Aug 9. Bioorg Med Chem Lett. 2011. PMID: 21875801
The structure of human CD23 and its interactions with IgE and CD21.
Hibbert RG, Teriete P, Grundy GJ, Beavil RL, Reljic R, Holers VM, Hannan JP, Sutton BJ, Gould HJ, McDonnell JM. Hibbert RG, et al. Among authors: mcdonnell jm. J Exp Med. 2005 Sep 19;202(6):751-60. doi: 10.1084/jem.20050811. J Exp Med. 2005. PMID: 16172256 Free PMC article.
543 results