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Susceptibility of sheep to experimental co-infection with the ancestral lineage of SARS-CoV-2 and its alpha variant.
Gaudreault NN, Cool K, Trujillo JD, Morozov I, Meekins DA, McDowell CD, Bold D, Carossino M, Balaraman V, Mitzel D, Kwon T, Madden DW, Artiaga BL, Pogranichniy R, Roman-Sosa G, Wilson WC, Balasuriya UB, Garcia-Sastre A, Richt JA. Gaudreault NN, et al. Among authors: mcdowell cd. bioRxiv. 2021 Nov 22:2021.11.15.468720. doi: 10.1101/2021.11.15.468720. Preprint. bioRxiv. 2021. PMID: 34816258 Free PMC article.
The N501Y mutation in SARS-CoV-2 spike leads to morbidity in obese and aged mice and is neutralized by convalescent and post-vaccination human sera.
Rathnasinghe R, Jangra S, Cupic A, Martínez-Romero C, Mulder LCF, Kehrer T, Yildiz S, Choi A, Mena I, De Vrieze J, Aslam S, Stadlbauer D, Meekins DA, McDowell CD, Balaraman V, Richt JA, De Geest BG, Miorin L, Krammer F, Simon V, García-Sastre A, Schotsaert M. Rathnasinghe R, et al. Among authors: mcdowell cd. medRxiv. 2021 Jan 20:2021.01.19.21249592. doi: 10.1101/2021.01.19.21249592. Preprint. medRxiv. 2021. PMID: 33501468 Free PMC article.