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Myristyl trimethyl ammonium bromide and octadecyl trimethyl ammonium bromide are surface-active small molecule dynamin inhibitors that block endocytosis mediated by dynamin I or dynamin II.
Quan A, McGeachie AB, Keating DJ, van Dam EM, Rusak J, Chau N, Malladi CS, Chen C, McCluskey A, Cousin MA, Robinson PJ. Quan A, et al. Among authors: mcgeachie ab. Mol Pharmacol. 2007 Dec;72(6):1425-39. doi: 10.1124/mol.107.034207. Epub 2007 Aug 16. Mol Pharmacol. 2007. PMID: 17702890
Pyrimidyn compounds: dual-action small molecule pyrimidine-based dynamin inhibitors.
McGeachie AB, Odell LR, Quan A, Daniel JA, Chau N, Hill TA, Gorgani NN, Keating DJ, Cousin MA, van Dam EM, Mariana A, Whiting A, Perera S, Novelle A, Young KA, Deane FM, Gilbert J, Sakoff JA, Chircop M, McCluskey A, Robinson PJ. McGeachie AB, et al. ACS Chem Biol. 2013 Jul 19;8(7):1507-18. doi: 10.1021/cb400137p. Epub 2013 May 30. ACS Chem Biol. 2013. PMID: 23642287
Building a better dynasore: the dyngo compounds potently inhibit dynamin and endocytosis.
McCluskey A, Daniel JA, Hadzic G, Chau N, Clayton EL, Mariana A, Whiting A, Gorgani NN, Lloyd J, Quan A, Moshkanbaryans L, Krishnan S, Perera S, Chircop M, von Kleist L, McGeachie AB, Howes MT, Parton RG, Campbell M, Sakoff JA, Wang X, Sun JY, Robertson MJ, Deane FM, Nguyen TH, Meunier FA, Cousin MA, Robinson PJ. McCluskey A, et al. Among authors: mcgeachie ab. Traffic. 2013 Dec;14(12):1272-89. doi: 10.1111/tra.12119. Epub 2013 Oct 9. Traffic. 2013. PMID: 24025110 Free PMC article.
Prodrugs of the Archetypal Dynamin Inhibitor Bis-T-22.
Odell LR, Robertson MJ, Young KA, McGeachie AB, Quan A, Robinson PJ, McCluskey A. Odell LR, et al. Among authors: mcgeachie ab. ChemMedChem. 2022 Dec 16;17(24):e202200400. doi: 10.1002/cmdc.202200400. Epub 2022 Nov 9. ChemMedChem. 2022. PMID: 36351775 Free PMC article.
23 results