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Efficient assessment of the utility of immortalized Fa2N-4 cells for cytochrome P450 (CYP) induction studies using multiplex quantitative reverse transcriptase-polymerase chain reaction (qRT-PCR) and substrate cassette methodologies.
Kenny JR, Chen L, McGinnity DF, Grime K, Shakesheff KM, Thomson B, Riley R. Kenny JR, et al. Among authors: mcginnity df. Xenobiotica. 2008 Dec;38(12):1500-17. doi: 10.1080/00498250802495846. Xenobiotica. 2008. PMID: 18989830
The pivotal role of hepatocytes in drug discovery.
Soars MG, McGinnity DF, Grime K, Riley RJ. Soars MG, et al. Among authors: mcginnity df. Chem Biol Interact. 2007 May 20;168(1):2-15. doi: 10.1016/j.cbi.2006.11.002. Epub 2006 Nov 18. Chem Biol Interact. 2007. PMID: 17208208 Review.
33 results