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Further evidence of IBD5/CARD15 (NOD2) epistasis in the susceptibility to ulcerative colitis.

McGovern DP, Van Heel DA, Negoro K, Ahmad T, Jewell DP. McGovern DP, et al. Am J Hum Genet. 2003 Dec;73(6):1465-6. doi: 10.1086/379745. Am J Hum Genet. 2003. PMID: 14655097 Free PMC article. No abstract available.

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NOD2 (CARD15), the first susceptibility gene for Crohn's disease.

McGovern DP, van Heel DA, Ahmad T, Jewell DP. McGovern DP, et al. Gut. 2001 Dec;49(6):752-4. doi: 10.1136/gut.49.6.752. Gut. 2001. PMID: 11709505 Free PMC article. No abstract available.

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Role of NOD2 variants in spondylarthritis.

Crane AM, Bradbury L, van Heel DA, McGovern DP, Brophy S, Rubin L, Siminovitch KA, Wordsworth BP, Calin A, Brown MA. Crane AM, et al. Among authors: mcgovern dp. Arthritis Rheum. 2002 Jun;46(6):1629-33. doi: 10.1002/art.10329. Arthritis Rheum. 2002. PMID: 12115195

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Fine mapping of the IBD1 locus did not identify Crohn disease-associated NOD2 variants: implications for complex disease genetics.

van Heel DA, McGovern DP, Cardon LR, Dechairo BM, Lench NJ, Carey AH, Jewell DP. van Heel DA, et al. Among authors: mcgovern dp. Am J Med Genet. 2002 Aug 15;111(3):253-9. doi: 10.1002/ajmg.10588. Am J Med Genet. 2002. PMID: 12210321

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Analysis of the IBD5 locus and potential gene-gene interactions in Crohn's disease.

Negoro K, McGovern DP, Kinouchi Y, Takahashi S, Lench NJ, Shimosegawa T, Carey A, Cardon LR, Jewell DP, van Heel DA. Negoro K, et al. Among authors: mcgovern dp. Gut. 2003 Apr;52(4):541-6. doi: 10.1136/gut.52.4.541. Gut. 2003. PMID: 12631666 Free PMC article.

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The IBD6 Crohn's disease locus demonstrates complex interactions with CARD15 and IBD5 disease-associated variants.

van Heel DA, Dechairo BM, Dawson G, McGovern DP, Negoro K, Carey AH, Cardon LR, Mackay I, Jewell DP, Lench NJ. van Heel DA, et al. Among authors: mcgovern dp. Hum Mol Genet. 2003 Oct 15;12(20):2569-75. doi: 10.1093/hmg/ddg281. Epub 2003 Aug 19. Hum Mol Genet. 2003. PMID: 12928481

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A common CTLA4 haplotype associated with coeliac disease.

Hunt KA, McGovern DP, Kumar PJ, Ghosh S, Travis SP, Walters JR, Jewell DP, Playford RJ, van Heel DA. Hunt KA, et al. Among authors: mcgovern dp. Eur J Hum Genet. 2005 Apr;13(4):440-4. doi: 10.1038/sj.ejhg.5201357. Eur J Hum Genet. 2005. PMID: 15657618

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Association between a complex insertion/deletion polymorphism in NOD1 (CARD4) and susceptibility to inflammatory bowel disease.

McGovern DP, Hysi P, Ahmad T, van Heel DA, Moffatt MF, Carey A, Cookson WO, Jewell DP. McGovern DP, et al. Hum Mol Genet. 2005 May 15;14(10):1245-50. doi: 10.1093/hmg/ddi135. Epub 2005 Mar 24. Hum Mol Genet. 2005. PMID: 15790594

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NOD2, not yet: con.

Brant SR, McGovern DP. Brant SR, et al. Among authors: mcgovern dp. Inflamm Bowel Dis. 2005 May;11(5):507-9. doi: 10.1097/01.mib.0000160739.38237.34. Inflamm Bowel Dis. 2005. PMID: 15867592 No abstract available.

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Ulcerative colitis-risk loci on chromosomes 1p36 and 12q15 found by genome-wide association study.

Silverberg MS, Cho JH, Rioux JD, McGovern DP, Wu J, Annese V, Achkar JP, Goyette P, Scott R, Xu W, Barmada MM, Klei L, Daly MJ, Abraham C, Bayless TM, Bossa F, Griffiths AM, Ippoliti AF, Lahaie RG, Latiano A, Paré P, Proctor DD, Regueiro MD, Steinhart AH, Targan SR, Schumm LP, Kistner EO, Lee AT, Gregersen PK, Rotter JI, Brant SR, Taylor KD, Roeder K, Duerr RH. Silverberg MS, et al. Among authors: mcgovern dp. Nat Genet. 2009 Feb;41(2):216-20. doi: 10.1038/ng.275. Epub 2009 Jan 4. Nat Genet. 2009. PMID: 19122664 Free PMC article.

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