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B-cell-directed CAR-T cell therapy activates CD8+ cytotoxic CARneg bystander T-cells in non-human primates and patients.
Kaminski J, Fleming RA, Alvarez-Calderon F, Winschel MB, McGuckin C, Ho EE, Eng F, Rui X, Keskula P, Cagnin L, Charles J, Zavistaski JM, Margossian SP, Kapadia M, Rottman JB, Lane J, Baumeister SHC, Tkachev V, Shalek A, Kean LS, Gerdemann U. Kaminski J, et al. Among authors: mcguckin c. Blood. 2024 Apr 1:blood.2023022717. doi: 10.1182/blood.2023022717. Online ahead of print. Blood. 2024. PMID: 38558106
Notch signaling drives intestinal graft-versus-host disease in mice and nonhuman primates.
Tkachev V, Vanderbeck A, Perkey E, Furlan SN, McGuckin C, Gómez Atria D, Gerdemann U, Rui X, Lane J, Hunt DJ, Zheng H, Colonna L, Hoffman M, Yu A, Outen R, Kelly S, Allman A, Koch U, Radtke F, Ludewig B, Burbach B, Shimizu Y, Panoskaltsis-Mortari A, Chen G, Carpenter SM, Harari O, Kuhnert F, Thurston G, Blazar BR, Kean LS, Maillard I. Tkachev V, et al. Among authors: mcguckin c. Sci Transl Med. 2023 Jun 28;15(702):eadd1175. doi: 10.1126/scitranslmed.add1175. Epub 2023 Jun 28. Sci Transl Med. 2023. PMID: 37379368
Supramolecular assembly of GSK3α as a cellular response to amino acid starvation.
Hinze L, Schreek S, Zeug A, Ibrahim NK, Fehlhaber B, Loxha L, Cinar B, Ponimaskin E, Degar J, McGuckin C, Chiosis G, Eckert C, Cario G, Bornhauser B, Bourquin JP, Stanulla M, Gutierrez A. Hinze L, et al. Among authors: mcguckin c. Mol Cell. 2022 Aug 4;82(15):2858-2870.e8. doi: 10.1016/j.molcel.2022.05.025. Epub 2022 Jun 21. Mol Cell. 2022. PMID: 35732190 Free PMC article.
94 results