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CAAX peptidomimetic FTI-244 decreases platelet-derived growth factor receptor tyrosine phosphorylation levels and inhibits stimulation of phosphatidylinositol 3-kinase but not mitogen-activated protein kinase.
McGuire TF, Qian Y, Blaskovich MA, Fossum RD, Sun J, Marlowe T, Corey SJ, Wathen SP, Vogt A, Hamilton AD, et al. McGuire TF, et al. Biochem Biophys Res Commun. 1995 Sep 5;214(1):295-303. doi: 10.1006/bbrc.1995.2287. Biochem Biophys Res Commun. 1995. PMID: 7669049
36 results