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First-in-Human Study With the Inhaled TLR9 Oligonucleotide Agonist AZD1419 Results in Interferon Responses in the Lung, and Is Safe and Well-Tolerated.
Jackson S, Candia AF, Delaney S, Floettmann S, Wong C, Campbell JD, Kell S, Lum J, Hessel EM, Traquina P, McHale M, Robinson I, Bell J, Fuhr R, Keeling D, Coffman RL. Jackson S, et al. Among authors: mchale m. Clin Pharmacol Ther. 2018 Aug;104(2):335-345. doi: 10.1002/cpt.938. Epub 2017 Dec 6. Clin Pharmacol Ther. 2018. PMID: 29134633 Clinical Trial.
Discovery of AZD-2098 and AZD-1678, Two Potent and Bioavailable CCR4 Receptor Antagonists.
Kindon N, Andrews G, Baxter A, Cheshire D, Hemsley P, Johnson T, Liu YZ, McGinnity D, McHale M, Mete A, Reuberson J, Roberts B, Steele J, Teobald B, Unitt J, Vaughan D, Walters I, Stocks MJ. Kindon N, et al. Among authors: mchale m. ACS Med Chem Lett. 2017 Sep 1;8(9):981-986. doi: 10.1021/acsmedchemlett.7b00315. eCollection 2017 Sep 14. ACS Med Chem Lett. 2017. PMID: 28947948 Free PMC article.
Different factors limit early- and late-season windows of opportunity for monarch development.
Yang LH, Swan K, Bastin E, Aguilar J, Cenzer M, Codd A, Gonzalez N, Hayes T, Higgins A, Lor X, Macharaga C, McMunn M, Oto K, Winarto N, Wong D, Yang T, Afridi N, Aguilar S, Allison A, Ambrose-Winters A, Amescua E, Apse M, Avoce N, Bastin K, Bolander E, Burroughs J, Cabrera C, Candy M, Cavett A, Cavett M, Chang L, Claret M, Coleman D, Concha J, Danzer P, DaRosa J, Dufresne A, Duisenberg C, Earl A, Eckey E, English M, Espejo A, Faith E, Fang A, Gamez A, Garcini J, Garcini J, Gilbert-Igelsrud G, Goedde-Matthews K, Grahn S, Guerra P, Guerra V, Hagedorn M, Hall K, Hall G, Hammond J, Hargadon C, Henley V, Hinesley S, Jacobs C, Johnson C, Johnson T, Johnson Z, Juchau E, Kaplan C, Katznelson A, Keeley R, Kubik T, Lam T, Lansing C, Lara A, Le V, Lee B, Lee K, Lemmo M, Lucio S, Luo A, Malakzay S, Mangney L, Martin J, Matern W, McConnell B, McHale M, McIsaac G, McLennan C, Milbrodt S, Mohammed M, Mooney-McCarthy M, Morgan L, Mullin C, Needles S, Nunes K, O'Keeffe F, O'Keeffe O, Osgood G, Padilla J, Padilla S, Palacio I, Panelli V, Paulson K, Pearson J, Perez T, Phrakonekham B, Pitsillides I, Preisler A, Preisler N, Ramirez H, Ransom S, Renaud C, Rocha T, Saris H, Schemrich R, Schoenig L, Sears S, Sharma A, Siu J, Spangler M, Standefer S, Strickland K, Stritzel M, Talbert E, Taylor S, Thomsen E, Toups K, Tran K, Tran H, Tuqiri M, Valdes S, VanVorhis G, Vue S, Wallace S, Whipple J, Yang P, Ye M, Yo D, Zeng Y. Yang LH, et al. Among authors: mchale m. Ecol Evol. 2022 Jul 11;12(7):e9039. doi: 10.1002/ece3.9039. eCollection 2022 Jul. Ecol Evol. 2022. PMID: 35845370 Free PMC article.
161 results