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Dual D2-receptor and beta2-adrenoceptor agonists for the treatment of airway diseases. 1. Discovery and biological evaluation of some 7-(2-aminoethyl)-4-hydroxybenzothiazol-2(3H)-one analogues.
Bonnert RV, Brown RC, Chapman D, Cheshire DR, Dixon J, Ince F, Kinchin EC, Lyons AJ, Davis AM, Hallam C, Harper ST, Unitt JF, Dougall IG, Jackson DM, McKechnie K, Young A, Simpson WT. Bonnert RV, et al. Among authors: mckechnie k. J Med Chem. 1998 Dec 3;41(25):4915-7. doi: 10.1021/jm980421f. J Med Chem. 1998. PMID: 9836607 No abstract available.
A three-state receptor model of agonist action.
Leff P, Scaramellini C, Law C, McKechnie K. Leff P, et al. Among authors: mckechnie k. Trends Pharmacol Sci. 1997 Oct;18(10):355-62. doi: 10.1016/s0165-6147(97)01105-x. Trends Pharmacol Sci. 1997. PMID: 9357320 Review.
23 results