McKeever BM - Search Results

1

Synthesis and antiviral activity of a series of HIV-1 protease inhibitors with functionality tethered to the P1 or P1' phenyl substituents: X-ray crystal structure assisted design.

Thompson WJ, Fitzgerald PM, Holloway MK, Emini EA, Darke PL, McKeever BM, Schleif WA, Quintero JC, Zugay JA, Tucker TJ, et al. Thompson WJ, et al. Among authors: mckeever bm. J Med Chem. 1992 May 15;35(10):1685-701. doi: 10.1021/jm00088a003. J Med Chem. 1992. PMID: 1588551

2

Crystallographic analysis of a complex between human immunodeficiency virus type 1 protease and acetyl-pepstatin at 2.0-A resolution.

Fitzgerald PM, McKeever BM, VanMiddlesworth JF, Springer JP, Heimbach JC, Leu CT, Herber WK, Dixon RA, Darke PL. Fitzgerald PM, et al. Among authors: mckeever bm. J Biol Chem. 1990 Aug 25;265(24):14209-19. J Biol Chem. 1990. PMID: 2201682 Free article.

3

Crystallization of the aspartylprotease from the human immunodeficiency virus, HIV-1.

McKeever BM, Navia MA, Fitzgerald PM, Springer JP, Leu CT, Heimbach JC, Herbert WK, Sigal IS, Darke PL. McKeever BM, et al. J Biol Chem. 1989 Feb 5;264(4):1919-21. J Biol Chem. 1989. PMID: 2644246 Free article.

4

Three-dimensional structure of aspartyl protease from human immunodeficiency virus HIV-1.

Navia MA, Fitzgerald PM, McKeever BM, Leu CT, Heimbach JC, Herber WK, Sigal IS, Darke PL, Springer JP. Navia MA, et al. Among authors: mckeever bm. Nature. 1989 Feb 16;337(6208):615-20. doi: 10.1038/337615a0. Nature. 1989. PMID: 2645523

5

The discovery of tetrahydrofluorenones as a new class of estrogen receptor beta-subtype selective ligands.

Wilkening RR, Ratcliffe RW, Tynebor EC, Wildonger KJ, Fried AK, Hammond ML, Mosley RT, Fitzgerald PM, Sharma N, McKeever BM, Nilsson S, Carlquist M, Thorsell A, Locco L, Katz R, Frisch K, Birzin ET, Wilkinson HA, Mitra S, Cai S, Hayes EC, Schaeffer JM, Rohrer SP. Wilkening RR, et al. Among authors: mckeever bm. Bioorg Med Chem Lett. 2006 Jul 1;16(13):3489-94. doi: 10.1016/j.bmcl.2006.03.098. Epub 2006 May 2. Bioorg Med Chem Lett. 2006. PMID: 16632357

6

Structure-based design and synthesis of 1,3-oxazinan-2-one inhibitors of 11β-hydroxysteroid dehydrogenase type 1.

Xu Z, Tice CM, Zhao W, Cacatian S, Ye YJ, Singh SB, Lindblom P, McKeever BM, Krosky PM, Kruk BA, Berbaum J, Harrison RK, Johnson JA, Bukhtiyarov Y, Panemangalore R, Scott BB, Zhao Y, Bruno JG, Togias J, Guo J, Guo R, Carroll PJ, McGeehan GM, Zhuang L, He W, Claremon DA. Xu Z, et al. Among authors: mckeever bm. J Med Chem. 2011 Sep 8;54(17):6050-62. doi: 10.1021/jm2005354. Epub 2011 Aug 4. J Med Chem. 2011. PMID: 21786805

7

Design and synthesis of alpha-aryloxyphenylacetic acid derivatives: a novel class of PPARalpha/gamma dual agonists with potent antihyperglycemic and lipid modulating activity.

Shi GQ, Dropinski JF, McKeever BM, Xu S, Becker JW, Berger JP, MacNaul KL, Elbrecht A, Zhou G, Doebber TW, Wang P, Chao YS, Forrest M, Heck JV, Moller DE, Jones AB. Shi GQ, et al. Among authors: mckeever bm. J Med Chem. 2005 Jun 30;48(13):4457-68. doi: 10.1021/jm0502135. J Med Chem. 2005. PMID: 15974597

8

New isomeric classes of topically active ocular hypotensive carbonic anhydrase inhibitors: 5-substituted thieno[2,3-b]thiophene-2-sulfonamides and 5-substituted thieno[3,2-b]thiophene-2-sulfonamides.

Prugh JD, Hartman GD, Mallorga PJ, McKeever BM, Michelson SR, Murcko MA, Schwam H, Smith RL, Sondey JM, Springer JP, et al. Prugh JD, et al. Among authors: mckeever bm. J Med Chem. 1991 Jun;34(6):1805-18. doi: 10.1021/jm00110a008. J Med Chem. 1991. PMID: 2061922

9

A role for the aspartyl protease from the human immunodeficiency virus type 1 (HIV-1) in the orchestration of virus assembly.

Navia MA, McKeever BM. Navia MA, et al. Among authors: mckeever bm. Ann N Y Acad Sci. 1990;616:73-85. doi: 10.1111/j.1749-6632.1990.tb17829.x. Ann N Y Acad Sci. 1990. PMID: 2078037 Review.

10

A new class of glycogen phosphorylase inhibitors.

Lu Z, Bohn J, Bergeron R, Deng Q, Ellsworth KP, Geissler WM, Harris G, McCann PE, McKeever B, Myers RW, Saperstein R, Willoughby CA, Yao J, Chapman K. Lu Z, et al. Bioorg Med Chem Lett. 2003 Nov 17;13(22):4125-8. doi: 10.1016/j.bmcl.2003.08.046. Bioorg Med Chem Lett. 2003. PMID: 14592521

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