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Genetic Coding Variant in GPR65 Alters Lysosomal pH and Links Lysosomal Dysfunction with Colitis Risk.
Lassen KG, McKenzie CI, Mari M, Murano T, Begun J, Baxt LA, Goel G, Villablanca EJ, Kuo SY, Huang H, Macia L, Bhan AK, Batten M, Daly MJ, Reggiori F, Mackay CR, Xavier RJ. Lassen KG, et al. Among authors: mckenzie ci. Immunity. 2016 Jun 21;44(6):1392-405. doi: 10.1016/j.immuni.2016.05.007. Epub 2016 Jun 7. Immunity. 2016. PMID: 27287411 Free PMC article.
Evidence that asthma is a developmental origin disease influenced by maternal diet and bacterial metabolites.
Thorburn AN, McKenzie CI, Shen S, Stanley D, Macia L, Mason LJ, Roberts LK, Wong CH, Shim R, Robert R, Chevalier N, Tan JK, Mariño E, Moore RJ, Wong L, McConville MJ, Tull DL, Wood LG, Murphy VE, Mattes J, Gibson PG, Mackay CR. Thorburn AN, et al. Among authors: mckenzie ci. Nat Commun. 2015 Jun 23;6:7320. doi: 10.1038/ncomms8320. Nat Commun. 2015. PMID: 26102221 Free article.
Gut microbial metabolites limit the frequency of autoimmune T cells and protect against type 1 diabetes.
Mariño E, Richards JL, McLeod KH, Stanley D, Yap YA, Knight J, McKenzie C, Kranich J, Oliveira AC, Rossello FJ, Krishnamurthy B, Nefzger CM, Macia L, Thorburn A, Baxter AG, Morahan G, Wong LH, Polo JM, Moore RJ, Lockett TJ, Clarke JM, Topping DL, Harrison LC, Mackay CR. Mariño E, et al. Nat Immunol. 2017 May;18(5):552-562. doi: 10.1038/ni.3713. Epub 2017 Mar 27. Nat Immunol. 2017. PMID: 28346408
An acetate-yielding diet imprints an immune and anti-microbial programme against enteric infection.
Yap YA, McLeod KH, McKenzie CI, Gavin PG, Davalos-Salas M, Richards JL, Moore RJ, Lockett TJ, Clarke JM, Eng VV, Pearson JS, Hamilton-Williams EE, Mackay CR, Mariño E. Yap YA, et al. Among authors: mckenzie ci. Clin Transl Immunology. 2021 Jan 15;10(1):e1233. doi: 10.1002/cti2.1233. eCollection 2021. Clin Transl Immunology. 2021. PMID: 33489123 Free PMC article.
27 results