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Stable expression of mammalian type A gamma-aminobutyric acid receptors in mouse cells: demonstration of functional assembly of benzodiazepine-responsive sites.
Hadingham KL, Harkness PC, McKernan RM, Quirk K, Le Bourdellès B, Horne AL, Kemp JA, Barnard EA, Ragan CI, Whiting PJ. Hadingham KL, et al. Among authors: mckernan rm. Proc Natl Acad Sci U S A. 1992 Jul 15;89(14):6378-82. doi: 10.1073/pnas.89.14.6378. Proc Natl Acad Sci U S A. 1992. PMID: 1321437 Free PMC article.
theta, a novel gamma-aminobutyric acid type A receptor subunit.
Bonnert TP, McKernan RM, Farrar S, le Bourdellès B, Heavens RP, Smith DW, Hewson L, Rigby MR, Sirinathsinghji DJ, Brown N, Wafford KA, Whiting PJ. Bonnert TP, et al. Among authors: mckernan rm. Proc Natl Acad Sci U S A. 1999 Aug 17;96(17):9891-6. doi: 10.1073/pnas.96.17.9891. Proc Natl Acad Sci U S A. 1999. PMID: 10449790 Free PMC article.
Sedation and anesthesia mediated by distinct GABA(A) receptor isoforms.
Reynolds DS, Rosahl TW, Cirone J, O'Meara GF, Haythornthwaite A, Newman RJ, Myers J, Sur C, Howell O, Rutter AR, Atack J, Macaulay AJ, Hadingham KL, Hutson PH, Belelli D, Lambert JJ, Dawson GR, McKernan R, Whiting PJ, Wafford KA. Reynolds DS, et al. J Neurosci. 2003 Sep 17;23(24):8608-17. doi: 10.1523/JNEUROSCI.23-24-08608.2003. J Neurosci. 2003. PMID: 13679430 Free PMC article.
3-Heteroaryl-2-pyridones: benzodiazepine site ligands with functional delectivity for alpha 2/alpha 3-subtypes of human GABA(A) receptor-ion channels.
Collins I, Moyes C, Davey WB, Rowley M, Bromidge FA, Quirk K, Atack JR, McKernan RM, Thompson SA, Wafford K, Dawson GR, Pike A, Sohal B, Tsou NN, Ball RG, Castro JL. Collins I, et al. Among authors: mckernan rm. J Med Chem. 2002 Apr 25;45(9):1887-900. doi: 10.1021/jm0110789. J Med Chem. 2002. PMID: 11960500
103 results