McKerrow JH - Search Results

1

A multienzyme network functions in intestinal protein digestion by a platyhelminth parasite.

Delcroix M, Sajid M, Caffrey CR, Lim KC, Dvorák J, Hsieh I, Bahgat M, Dissous C, McKerrow JH. Delcroix M, et al. Among authors: mckerrow jh. J Biol Chem. 2006 Dec 22;281(51):39316-29. doi: 10.1074/jbc.M607128200. Epub 2006 Oct 6. J Biol Chem. 2006. PMID: 17028179 Free article.

2

Functional expression and characterization of Schistosoma mansoni cathepsin B and its trans-activation by an endogenous asparaginyl endopeptidase.

Sajid M, McKerrow JH, Hansell E, Mathieu MA, Lucas KD, Hsieh I, Greenbaum D, Bogyo M, Salter JP, Lim KC, Franklin C, Kim JH, Caffrey CR. Sajid M, et al. Among authors: mckerrow jh. Mol Biochem Parasitol. 2003 Sep;131(1):65-75. doi: 10.1016/s0166-6851(03)00194-4. Mol Biochem Parasitol. 2003. PMID: 12967713

3

Homology modeling and SAR analysis of Schistosoma japonicum cathepsin D (SjCD) with statin inhibitors identify a unique active site steric barrier with potential for the design of specific inhibitors.

Caffrey CR, Placha L, Barinka C, Hradilek M, Dostál J, Sajid M, McKerrow JH, Majer P, Konvalinka J, Vondrásek J. Caffrey CR, et al. Among authors: mckerrow jh. Biol Chem. 2005 Apr;386(4):339-49. doi: 10.1515/BC.2005.041. Biol Chem. 2005. PMID: 15899696

4

A parasite cysteine protease is key to host protein degradation and iron acquisition.

O'Brien TC, Mackey ZB, Fetter RD, Choe Y, O'Donoghue AJ, Zhou M, Craik CS, Caffrey CR, McKerrow JH. O'Brien TC, et al. Among authors: mckerrow jh. J Biol Chem. 2008 Oct 24;283(43):28934-43. doi: 10.1074/jbc.M805824200. Epub 2008 Aug 13. J Biol Chem. 2008. PMID: 18701454 Free PMC article.

5

SmCL3, a gastrodermal cysteine protease of the human blood fluke Schistosoma mansoni.

Dvorák J, Mashiyama ST, Sajid M, Braschi S, Delcroix M, Schneider EL, McKerrow WH, Bahgat M, Hansell E, Babbitt PC, Craik CS, McKerrow JH, Caffrey CR. Dvorák J, et al. Among authors: mckerrow wh, mckerrow jh. PLoS Negl Trop Dis. 2009 Jun 2;3(6):e449. doi: 10.1371/journal.pntd.0000449. PLoS Negl Trop Dis. 2009. PMID: 19488406 Free PMC article.

6

Vinyl sulfones as antiparasitic agents and a structural basis for drug design.

Kerr ID, Lee JH, Farady CJ, Marion R, Rickert M, Sajid M, Pandey KC, Caffrey CR, Legac J, Hansell E, McKerrow JH, Craik CS, Rosenthal PJ, Brinen LS. Kerr ID, et al. Among authors: mckerrow jh. J Biol Chem. 2009 Sep 18;284(38):25697-703. doi: 10.1074/jbc.M109.014340. Epub 2009 Jul 20. J Biol Chem. 2009. PMID: 19620707 Free PMC article.

7

Structural basis for inhibition of cathepsin B drug target from the human blood fluke, Schistosoma mansoni.

Jílková A, Řezáčová P, Lepšík M, Horn M, Váchová J, Fanfrlík J, Brynda J, McKerrow JH, Caffrey CR, Mareš M. Jílková A, et al. Among authors: mckerrow jh. J Biol Chem. 2011 Oct 14;286(41):35770-35781. doi: 10.1074/jbc.M111.271304. Epub 2011 Aug 10. J Biol Chem. 2011. PMID: 21832058 Free PMC article.

8

A blood fluke serine protease inhibitor regulates an endogenous larval elastase.

Lopez Quezada L, Sajid M, Lim KC, McKerrow JH. Lopez Quezada L, et al. Among authors: mckerrow jh. J Biol Chem. 2012 Mar 2;287(10):7074-83. doi: 10.1074/jbc.M111.313304. Epub 2011 Dec 15. J Biol Chem. 2012. PMID: 22174417 Free PMC article.

9

Schistosome invasion of human skin and degradation of dermal elastin are mediated by a single serine protease.

Salter JP, Lim KC, Hansell E, Hsieh I, McKerrow JH. Salter JP, et al. Among authors: mckerrow jh. J Biol Chem. 2000 Dec 8;275(49):38667-73. doi: 10.1074/jbc.M006997200. J Biol Chem. 2000. PMID: 10993899 Free article.

10

Substrate specificity of schistosome versus human legumain determined by P1-P3 peptide libraries.

Mathieu MA, Bogyo M, Caffrey CR, Choe Y, Lee J, Chapman H, Sajid M, Craik CS, McKerrow JH. Mathieu MA, et al. Among authors: mckerrow jh. Mol Biochem Parasitol. 2002 Apr 30;121(1):99-105. doi: 10.1016/s0166-6851(02)00026-9. Mol Biochem Parasitol. 2002. PMID: 11985866

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