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326 results
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Drug discovery and development for neglected parasitic diseases.
Renslo AR, McKerrow JH. Renslo AR, et al. Among authors: mckerrow jh. Nat Chem Biol. 2006 Dec;2(12):701-10. doi: 10.1038/nchembio837. Nat Chem Biol. 2006. PMID: 17108988 Review.
Tumour necrosis factor alpha restores granulomas and induces parasite egg-laying in schistosome-infected SCID mice.
Amiri P, Locksley RM, Parslow TG, Sadick M, Rector E, Ritter D, McKerrow JH. Amiri P, et al. Among authors: mckerrow jh. Nature. 1992 Apr 16;356(6370):604-7. doi: 10.1038/356604a0. Nature. 1992. PMID: 1560843
Parasite proteases.
McKerrow JH. McKerrow JH. Exp Parasitol. 1989 Jan;68(1):111-5. doi: 10.1016/0014-4894(89)90016-7. Exp Parasitol. 1989. PMID: 2645160 Review. No abstract available.
The crystal structure of cruzain: a therapeutic target for Chagas' disease.
McGrath ME, Eakin AE, Engel JC, McKerrow JH, Craik CS, Fletterick RJ. McGrath ME, et al. Among authors: mckerrow jh. J Mol Biol. 1995 Mar 24;247(2):251-9. doi: 10.1006/jmbi.1994.0137. J Mol Biol. 1995. PMID: 7707373
The proteases and pathogenicity of parasitic protozoa.
McKerrow JH, Sun E, Rosenthal PJ, Bouvier J. McKerrow JH, et al. Annu Rev Microbiol. 1993;47:821-53. doi: 10.1146/annurev.mi.47.100193.004133. Annu Rev Microbiol. 1993. PMID: 8257117 Review.
Using scid mice to study parasitic diseases.
McKerrow JH, Ritter DM. McKerrow JH, et al. Lab Anim Sci. 1993 Apr;43(2):136-8. Lab Anim Sci. 1993. PMID: 8320960 Review.
Structure-based design of parasitic protease inhibitors.
Li R, Chen X, Gong B, Selzer PM, Li Z, Davidson E, Kurzban G, Miller RE, Nuzum EO, McKerrow JH, Fletterick RJ, Gillmor SA, Craik CS, Kuntz ID, Cohen FE, Kenyon GL. Li R, et al. Among authors: mckerrow jh. Bioorg Med Chem. 1996 Sep;4(9):1421-7. doi: 10.1016/0968-0896(96)00136-8. Bioorg Med Chem. 1996. PMID: 8894100
Parasitic infections--molecular diagnosis and rational drug design.
McKerrow JH. McKerrow JH. Biologicals. 1996 Sep;24(3):207-8. doi: 10.1006/biol.1996.0028. Biologicals. 1996. PMID: 8978920 No abstract available.
Cysteine protease inhibitors as chemotherapy for parasitic infections.
McKerrow JH, Engel JC, Caffrey CR. McKerrow JH, et al. Bioorg Med Chem. 1999 Apr;7(4):639-44. doi: 10.1016/s0968-0896(99)00008-5. Bioorg Med Chem. 1999. PMID: 10353643 Review.
Development of cysteine protease inhibitors as chemotherapy for parasitic diseases: insights on safety, target validation, and mechanism of action.
McKerrow JH. McKerrow JH. Int J Parasitol. 1999 Jun;29(6):833-7. doi: 10.1016/s0020-7519(99)00044-2. Int J Parasitol. 1999. PMID: 10480720 Review.
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