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Phenotypic screens as a renewed approach for drug discovery.
Zheng W, Thorne N, McKew JC. Zheng W, et al. Among authors: mckew jc. Drug Discov Today. 2013 Nov;18(21-22):1067-73. doi: 10.1016/j.drudis.2013.07.001. Epub 2013 Jul 9. Drug Discov Today. 2013. PMID: 23850704 Free PMC article. Review.
An open source pharma roadmap.
Balasegaram M, Kolb P, McKew J, Menon J, Olliaro P, Sablinski T, Thomas Z, Todd MH, Torreele E, Wilbanks J. Balasegaram M, et al. PLoS Med. 2017 Apr 18;14(4):e1002276. doi: 10.1371/journal.pmed.1002276. eCollection 2017 Apr. PLoS Med. 2017. PMID: 28419094 Free PMC article.
Collaborative development of 2-hydroxypropyl-β-cyclodextrin for the treatment of Niemann-Pick type C1 disease.
Ottinger EA, Kao ML, Carrillo-Carrasco N, Yanjanin N, Shankar RK, Janssen M, Brewster M, Scott I, Xu X, Cradock J, Terse P, Dehdashti SJ, Marugan J, Zheng W, Portilla L, Hubbs A, Pavan WJ, Heiss J, Vite CH, Walkley SU, Ory DS, Silber SA, Porter FD, Austin CP, McKew JC. Ottinger EA, et al. Among authors: mckew jc. Curr Top Med Chem. 2014;14(3):330-9. doi: 10.2174/1568026613666131127160118. Curr Top Med Chem. 2014. PMID: 24283970 Free PMC article. Review.
A phenotypic compound screening assay for lysosomal storage diseases.
Xu M, Liu K, Swaroop M, Sun W, Dehdashti SJ, McKew JC, Zheng W. Xu M, et al. Among authors: mckew jc. J Biomol Screen. 2014 Jan;19(1):168-75. doi: 10.1177/1087057113501197. Epub 2013 Aug 27. J Biomol Screen. 2014. PMID: 23983233 Free PMC article.
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