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Page 1
Crosslinking and mechanical properties significantly influence cell attachment, proliferation, and migration within collagen glycosaminoglycan scaffolds.
Haugh MG, Murphy CM, McKiernan RC, Altenbuchner C, O'Brien FJ. Haugh MG, et al. Among authors: mckiernan rc. Tissue Eng Part A. 2011 May;17(9-10):1201-8. doi: 10.1089/ten.TEA.2010.0590. Epub 2011 Jan 17. Tissue Eng Part A. 2011. PMID: 21155630
Transgenic overexpression of 14-3-3 zeta protects hippocampus against endoplasmic reticulum stress and status epilepticus in vivo.
Brennan GP, Jimenez-Mateos EM, McKiernan RC, Engel T, Tzivion G, Henshall DC. Brennan GP, et al. Among authors: mckiernan rc. PLoS One. 2013;8(1):e54491. doi: 10.1371/journal.pone.0054491. Epub 2013 Jan 24. PLoS One. 2013. PMID: 23359526 Free PMC article.
Bmf upregulation through the AMP-activated protein kinase pathway may protect the brain from seizure-induced cell death.
Moran C, Sanz-Rodriguez A, Jimenez-Pacheco A, Martinez-Villareal J, McKiernan RC, Jimenez-Mateos EM, Mooney C, Woods I, Prehn JH, Henshall DC, Engel T. Moran C, et al. Among authors: mckiernan rc. Cell Death Dis. 2013 Apr 25;4(4):e606. doi: 10.1038/cddis.2013.136. Cell Death Dis. 2013. PMID: 23618904 Free PMC article.
Expression profiling the microRNA response to epileptic preconditioning identifies miR-184 as a modulator of seizure-induced neuronal death.
McKiernan RC, Jimenez-Mateos EM, Sano T, Bray I, Stallings RL, Simon RP, Henshall DC. McKiernan RC, et al. Exp Neurol. 2012 Oct;237(2):346-54. doi: 10.1016/j.expneurol.2012.06.029. Epub 2012 Jul 5. Exp Neurol. 2012. PMID: 22771761 Free PMC article.
Reduced mature microRNA levels in association with dicer loss in human temporal lobe epilepsy with hippocampal sclerosis.
McKiernan RC, Jimenez-Mateos EM, Bray I, Engel T, Brennan GP, Sano T, Michalak Z, Moran C, Delanty N, Farrell M, O'Brien D, Meller R, Simon RP, Stallings RL, Henshall DC. McKiernan RC, et al. PLoS One. 2012;7(5):e35921. doi: 10.1371/journal.pone.0035921. Epub 2012 May 15. PLoS One. 2012. PMID: 22615744 Free PMC article.
miRNA Expression profile after status epilepticus and hippocampal neuroprotection by targeting miR-132.
Jimenez-Mateos EM, Bray I, Sanz-Rodriguez A, Engel T, McKiernan RC, Mouri G, Tanaka K, Sano T, Saugstad JA, Simon RP, Stallings RL, Henshall DC. Jimenez-Mateos EM, et al. Among authors: mckiernan rc. Am J Pathol. 2011 Nov;179(5):2519-32. doi: 10.1016/j.ajpath.2011.07.036. Epub 2011 Sep 23. Am J Pathol. 2011. PMID: 21945804 Free PMC article.
Antagomirs targeting microRNA-134 increase hippocampal pyramidal neuron spine volume in vivo and protect against pilocarpine-induced status epilepticus.
Jimenez-Mateos EM, Engel T, Merino-Serrais P, Fernaud-Espinosa I, Rodriguez-Alvarez N, Reynolds J, Reschke CR, Conroy RM, McKiernan RC, deFelipe J, Henshall DC. Jimenez-Mateos EM, et al. Among authors: mckiernan rc. Brain Struct Funct. 2015 Jul;220(4):2387-99. doi: 10.1007/s00429-014-0798-5. Epub 2014 May 30. Brain Struct Funct. 2015. PMID: 24874920
Silencing microRNA-134 produces neuroprotective and prolonged seizure-suppressive effects.
Jimenez-Mateos EM, Engel T, Merino-Serrais P, McKiernan RC, Tanaka K, Mouri G, Sano T, O'Tuathaigh C, Waddington JL, Prenter S, Delanty N, Farrell MA, O'Brien DF, Conroy RM, Stallings RL, DeFelipe J, Henshall DC. Jimenez-Mateos EM, et al. Among authors: mckiernan rc. Nat Med. 2012 Jul;18(7):1087-94. doi: 10.1038/nm.2834. Nat Med. 2012. PMID: 22683779 Free PMC article.
Transcriptional Response of Polycomb Group Genes to Status Epilepticus in Mice is Modified by Prior Exposure to Epileptic Preconditioning.
Reynolds JP, Miller-Delaney SF, Jimenez-Mateos EM, Sano T, McKiernan RC, Simon RP, Henshall DC. Reynolds JP, et al. Among authors: mckiernan rc. Front Neurol. 2015 Mar 10;6:46. doi: 10.3389/fneur.2015.00046. eCollection 2015. Front Neurol. 2015. PMID: 25806020 Free PMC article.
Differential DNA methylation profiles of coding and non-coding genes define hippocampal sclerosis in human temporal lobe epilepsy.
Miller-Delaney SF, Bryan K, Das S, McKiernan RC, Bray IM, Reynolds JP, Gwinn R, Stallings RL, Henshall DC. Miller-Delaney SF, et al. Among authors: mckiernan rc. Brain. 2015 Mar;138(Pt 3):616-31. doi: 10.1093/brain/awu373. Epub 2014 Dec 30. Brain. 2015. PMID: 25552301 Free PMC article.