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Cytochrome P450-dependent metabolism of gefitinib.
McKillop D, McCormick AD, Millar A, Miles GS, Phillips PJ, Hutchison M. McKillop D, et al. Xenobiotica. 2005 Jan;35(1):39-50. doi: 10.1080/00498250400026464. Xenobiotica. 2005. PMID: 15788367
In vitro metabolism of gefitinib in human liver microsomes.
McKillop D, McCormick AD, Miles GS, Phillips PJ, Pickup KJ, Bushby N, Hutchison M. McKillop D, et al. Xenobiotica. 2004 Nov-Dec;34(11-12):983-1000. doi: 10.1080/02772240400015222. Xenobiotica. 2004. PMID: 15801543
Discovery, synthesis, and in vivo activity of a new class of pyrazoloquinazolines as selective inhibitors of aurora B kinase.
Mortlock AA, Foote KM, Heron NM, Jung FH, Pasquet G, Lohmann JJ, Warin N, Renaud F, De Savi C, Roberts NJ, Johnson T, Dousson CB, Hill GB, Perkins D, Hatter G, Wilkinson RW, Wedge SR, Heaton SP, Odedra R, Keen NJ, Crafter C, Brown E, Thompson K, Brightwell S, Khatri L, Brady MC, Kearney S, McKillop D, Rhead S, Parry T, Green S. Mortlock AA, et al. Among authors: mckillop d. J Med Chem. 2007 May 3;50(9):2213-24. doi: 10.1021/jm061335f. Epub 2007 Mar 21. J Med Chem. 2007. PMID: 17373783
56 results