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Preexisting memory CD4+ T cells contribute to the primary response in an HIV-1 vaccine trial.
Campion SL, Brenna E, Thomson E, Fischer W, Ladell K, McLaren JE, Price DA, Frahm N, McElrath JM, Cohen KW, Maenza JR, Walsh SR, Baden LR, Haynes BF, Korber B, Borrow P, McMichael AJ. Campion SL, et al. Among authors: mclaren je. J Clin Invest. 2021 Dec 1;131(23):e150823. doi: 10.1172/JCI150823. J Clin Invest. 2021. PMID: 34850742 Free PMC article. Clinical Trial.
Avidity of influenza-specific memory CD8+ T-cell populations decays over time compromising antiviral immunity.
Humphreys IR, Clement M, Marsden M, Ladell K, McLaren JE, Smart K, Hindley JP, Bridgeman HM, van den Berg HA, Price DA, Ager A, Wooldridge L, Godkin A, Gallimore AM. Humphreys IR, et al. Among authors: mclaren je. Eur J Immunol. 2012 Dec;42(12):3235-42. doi: 10.1002/eji.201242575. Epub 2012 Oct 16. Eur J Immunol. 2012. PMID: 22965681 Free PMC article.
A molecular basis for the control of preimmune escape variants by HIV-specific CD8+ T cells.
Ladell K, Hashimoto M, Iglesias MC, Wilmann PG, McLaren JE, Gras S, Chikata T, Kuse N, Fastenackels S, Gostick E, Bridgeman JS, Venturi V, Arkoub ZA, Agut H, van Bockel DJ, Almeida JR, Douek DC, Meyer L, Venet A, Takiguchi M, Rossjohn J, Price DA, Appay V. Ladell K, et al. Among authors: mclaren je. Immunity. 2013 Mar 21;38(3):425-36. doi: 10.1016/j.immuni.2012.11.021. Immunity. 2013. PMID: 23521884 Free article.
Programmed death-1 expression on HIV-1-specific CD8+ T cells is shaped by epitope specificity, T-cell receptor clonotype usage and antigen load.
Kløverpris HN, McGregor R, McLaren JE, Ladell K, Stryhn A, Koofhethile C, Brener J, Chen F, Riddell L, Graziano L, Klenerman P, Leslie A, Buus S, Price DA, Goulder P. Kløverpris HN, et al. Among authors: mclaren je. AIDS. 2014 Sep 10;28(14):2007-21. doi: 10.1097/QAD.0000000000000362. AIDS. 2014. PMID: 24906112 Free PMC article.
MR1-restricted MAIT cells display ligand discrimination and pathogen selectivity through distinct T cell receptor usage.
Gold MC, McLaren JE, Reistetter JA, Smyk-Pearson S, Ladell K, Swarbrick GM, Yu YY, Hansen TH, Lund O, Nielsen M, Gerritsen B, Kesmir C, Miles JJ, Lewinsohn DA, Price DA, Lewinsohn DM. Gold MC, et al. Among authors: mclaren je. J Exp Med. 2014 Jul 28;211(8):1601-10. doi: 10.1084/jem.20140507. Epub 2014 Jul 21. J Exp Med. 2014. PMID: 25049333 Free PMC article.
β-cell-specific CD8 T cell phenotype in type 1 diabetes reflects chronic autoantigen exposure.
Skowera A, Ladell K, McLaren JE, Dolton G, Matthews KK, Gostick E, Kronenberg-Versteeg D, Eichmann M, Knight RR, Heck S, Powrie J, Bingley PJ, Dayan CM, Miles JJ, Sewell AK, Price DA, Peakman M. Skowera A, et al. Among authors: mclaren je. Diabetes. 2015 Mar;64(3):916-925. doi: 10.2337/db14-0332. Epub 2014 Sep 23. Diabetes. 2015. PMID: 25249579 Free PMC article.
Role of naive-derived T memory stem cells in T-cell reconstitution following allogeneic transplantation.
Roberto A, Castagna L, Zanon V, Bramanti S, Crocchiolo R, McLaren JE, Gandolfi S, Tentorio P, Sarina B, Timofeeva I, Santoro A, Carlo-Stella C, Bruno B, Carniti C, Corradini P, Gostick E, Ladell K, Price DA, Roederer M, Mavilio D, Lugli E. Roberto A, et al. Among authors: mclaren je. Blood. 2015 Apr 30;125(18):2855-64. doi: 10.1182/blood-2014-11-608406. Epub 2015 Mar 5. Blood. 2015. PMID: 25742699 Free PMC article. Clinical Trial.
64 results