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Targeting dynorphin/kappa opioid receptor systems to treat alcohol abuse and dependence.
Walker BM, Valdez GR, McLaughlin JP, Bakalkin G. Walker BM, et al. Among authors: McLaughlin JP. Alcohol. 2012 Jun;46(4):359-70. doi: 10.1016/j.alcohol.2011.10.006. Epub 2012 Mar 27. Alcohol. 2012. PMID: 22459870 Free PMC article. Review.
Jay McLaughlin focused on the role of KORs in repeated stress-induced potentiation of alcohol reward and increased alcohol consumption. ...
Jay McLaughlin focused on the role of KORs in repeated stress-induced potentiation of alcohol reward and increased alcohol consumptio …
Neuropathic pain activates the endogenous kappa opioid system in mouse spinal cord and induces opioid receptor tolerance.
Xu M, Petraschka M, McLaughlin JP, Westenbroek RE, Caron MG, Lefkowitz RJ, Czyzyk TA, Pintar JE, Terman GW, Chavkin C. Xu M, et al. Among authors: McLaughlin JP. Version 2. J Neurosci. 2004 May 12;24(19):4576-84. doi: 10.1523/JNEUROSCI.5552-03.2004. J Neurosci. 2004. PMID: 15140929 Free PMC article.
Alanine analogues of [D-Trp]CJ-15,208: novel opioid activity profiles and prevention of drug- and stress-induced reinstatement of cocaine-seeking behaviour.
Aldrich JV, Senadheera SN, Ross NC, Reilley KA, Ganno ML, Eans SE, Murray TF, McLaughlin JP. Aldrich JV, et al. Among authors: McLaughlin JP. Br J Pharmacol. 2014 Jul;171(13):3212-22. doi: 10.1111/bph.12664. Br J Pharmacol. 2014. PMID: 24588614 Free PMC article.
Effects of the kappa opioid receptor antagonist, norbinaltorphimine, on stress and drug-induced reinstatement of nicotine-conditioned place preference in mice.
Jackson KJ, McLaughlin JP, Carroll FI, Damaj MI. Jackson KJ, et al. Among authors: McLaughlin JP. Psychopharmacology (Berl). 2013 Apr;226(4):763-8. doi: 10.1007/s00213-012-2716-y. Epub 2012 Apr 20. Psychopharmacology (Berl). 2013. PMID: 22526543 Free PMC article.
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