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Kratom policy: The challenge of balancing therapeutic potential with public safety.
Prozialeck WC, Avery BA, Boyer EW, Grundmann O, Henningfield JE, Kruegel AC, McMahon LR, McCurdy CR, Swogger MT, Veltri CA, Singh D. Prozialeck WC, et al. Among authors: mcmahon lr. Int J Drug Policy. 2019 Aug;70:70-77. doi: 10.1016/j.drugpo.2019.05.003. Epub 2019 May 16. Int J Drug Policy. 2019. PMID: 31103778 Free PMC article.
Investigation of the Adrenergic and Opioid Binding Affinities, Metabolic Stability, Plasma Protein Binding Properties, and Functional Effects of Selected Indole-Based Kratom Alkaloids.
Obeng S, Kamble SH, Reeves ME, Restrepo LF, Patel A, Behnke M, Chear NJ, Ramanathan S, Sharma A, León F, Hiranita T, Avery BA, McMahon LR, McCurdy CR. Obeng S, et al. Among authors: mcmahon lr. J Med Chem. 2020 Jan 9;63(1):433-439. doi: 10.1021/acs.jmedchem.9b01465. Epub 2019 Dec 27. J Med Chem. 2020. PMID: 31834797 Free PMC article.
Bioanalytical method development and validation of corynantheidine, a kratom alkaloid, using UPLC-MS/MS, and its application to preclinical pharmacokinetic studies.
King TI, Sharma A, Kamble SH, León F, Berthold EC, Popa R, Cerlati O, Prentice BM, McMahon LR, McCurdy CR, Avery BA. King TI, et al. Among authors: mcmahon lr. J Pharm Biomed Anal. 2020 Feb 20;180:113019. doi: 10.1016/j.jpba.2019.113019. Epub 2019 Dec 5. J Pharm Biomed Anal. 2020. PMID: 31838282 Free PMC article.
Pharmacokinetics and Safety of Mitragynine in Beagle Dogs.
Maxwell EA, King TI, Kamble SH, Raju KSR, Berthold EC, León F, Avery BA, McMahon LR, McCurdy CR, Sharma A. Maxwell EA, et al. Among authors: mcmahon lr. Planta Med. 2020 Nov;86(17):1278-1285. doi: 10.1055/a-1212-5475. Epub 2020 Jul 21. Planta Med. 2020. PMID: 32693425 Free PMC article.
Evaluation of the rewarding effects of mitragynine and 7-hydroxymitragynine in an intracranial self-stimulation procedure in male and female rats.
Behnood-Rod A, Chellian R, Wilson R, Hiranita T, Sharma A, Leon F, McCurdy CR, McMahon LR, Bruijnzeel AW. Behnood-Rod A, et al. Among authors: mcmahon lr. Drug Alcohol Depend. 2020 Oct 1;215:108235. doi: 10.1016/j.drugalcdep.2020.108235. Epub 2020 Aug 18. Drug Alcohol Depend. 2020. PMID: 32889450 Free PMC article.
Current and Future Potential Impact of COVID-19 on Kratom (Mitragyna speciosa Korth.) Supply and Use.
Singh D, Brown PN, Cinosi E, Corazza O, Henningfield JE, Garcia-Romeu A, McCurdy CR, McMahon LR, Prozialeck WC, Smith KE, Swogger MT, Veltri C, Walsh Z, Grundmann O. Singh D, et al. Among authors: mcmahon lr. Front Psychiatry. 2020 Nov 26;11:574483. doi: 10.3389/fpsyt.2020.574483. eCollection 2020. Front Psychiatry. 2020. PMID: 33324252 Free PMC article.
Metabolism of a Kratom Alkaloid Metabolite in Human Plasma Increases Its Opioid Potency and Efficacy.
Kamble SH, León F, King TI, Berthold EC, Lopera-Londoño C, Siva Rama Raju K, Hampson AJ, Sharma A, Avery BA, McMahon LR, McCurdy CR. Kamble SH, et al. Among authors: mcmahon lr. ACS Pharmacol Transl Sci. 2020 Jul 31;3(6):1063-1068. doi: 10.1021/acsptsci.0c00075. eCollection 2020 Dec 11. ACS Pharmacol Transl Sci. 2020. PMID: 33344889 Free PMC article.
136 results