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Rapid creation and quantitative monitoring of high coverage shRNA libraries.
Bassik MC, Lebbink RJ, Churchman LS, Ingolia NT, Patena W, LeProust EM, Schuldiner M, Weissman JS, McManus MT. Bassik MC, et al. Among authors: mcmanus mt. Nat Methods. 2009 Jun;6(6):443-5. doi: 10.1038/nmeth.1330. Epub 2009 May 17. Nat Methods. 2009. PMID: 19448642 Free PMC article.
Up-regulation of miR-21 by HER2/neu signaling promotes cell invasion.
Huang TH, Wu F, Loeb GB, Hsu R, Heidersbach A, Brincat A, Horiuchi D, Lebbink RJ, Mo YY, Goga A, McManus MT. Huang TH, et al. Among authors: mcmanus mt. J Biol Chem. 2009 Jul 3;284(27):18515-24. doi: 10.1074/jbc.M109.006676. Epub 2009 May 6. J Biol Chem. 2009. PMID: 19419954 Free PMC article.
Widespread RNA 3'-end oligouridylation in mammals.
Choi YS, Patena W, Leavitt AD, McManus MT. Choi YS, et al. Among authors: mcmanus mt. RNA. 2012 Mar;18(3):394-401. doi: 10.1261/rna.029306.111. Epub 2012 Jan 30. RNA. 2012. PMID: 22291204 Free PMC article.
Next-generation NAMPT inhibitors identified by sequential high-throughput phenotypic chemical and functional genomic screens.
Matheny CJ, Wei MC, Bassik MC, Donnelly AJ, Kampmann M, Iwasaki M, Piloto O, Solow-Cordero DE, Bouley DM, Rau R, Brown P, McManus MT, Weissman JS, Cleary ML. Matheny CJ, et al. Among authors: mcmanus mt. Chem Biol. 2013 Nov 21;20(11):1352-63. doi: 10.1016/j.chembiol.2013.09.014. Epub 2013 Oct 31. Chem Biol. 2013. PMID: 24183972 Free PMC article.
Massively parallel functional annotation of 3' untranslated regions.
Zhao W, Pollack JL, Blagev DP, Zaitlen N, McManus MT, Erle DJ. Zhao W, et al. Among authors: mcmanus mt. Nat Biotechnol. 2014 Apr;32(4):387-91. doi: 10.1038/nbt.2851. Epub 2014 Mar 16. Nat Biotechnol. 2014. PMID: 24633241 Free PMC article.
A high-coverage shRNA screen identifies TMEM129 as an E3 ligase involved in ER-associated protein degradation.
van de Weijer ML, Bassik MC, Luteijn RD, Voorburg CM, Lohuis MA, Kremmer E, Hoeben RC, LeProust EM, Chen S, Hoelen H, Ressing ME, Patena W, Weissman JS, McManus MT, Wiertz EJ, Lebbink RJ. van de Weijer ML, et al. Among authors: mcmanus mt. Nat Commun. 2014 May 8;5:3832. doi: 10.1038/ncomms4832. Nat Commun. 2014. PMID: 24807418 Free PMC article.
Systematic identification of barriers to human iPSC generation.
Qin H, Diaz A, Blouin L, Lebbink RJ, Patena W, Tanbun P, LeProust EM, McManus MT, Song JS, Ramalho-Santos M. Qin H, et al. Among authors: mcmanus mt. Cell. 2014 Jul 17;158(2):449-461. doi: 10.1016/j.cell.2014.05.040. Cell. 2014. PMID: 25036638 Free PMC article.
Integrative analysis of 111 reference human epigenomes.
Roadmap Epigenomics Consortium; Kundaje A, Meuleman W, Ernst J, Bilenky M, Yen A, Heravi-Moussavi A, Kheradpour P, Zhang Z, Wang J, Ziller MJ, Amin V, Whitaker JW, Schultz MD, Ward LD, Sarkar A, Quon G, Sandstrom RS, Eaton ML, Wu YC, Pfenning AR, Wang X, Claussnitzer M, Liu Y, Coarfa C, Harris RA, Shoresh N, Epstein CB, Gjoneska E, Leung D, Xie W, Hawkins RD, Lister R, Hong C, Gascard P, Mungall AJ, Moore R, Chuah E, Tam A, Canfield TK, Hansen RS, Kaul R, Sabo PJ, Bansal MS, Carles A, Dixon JR, Farh KH, Feizi S, Karlic R, Kim AR, Kulkarni A, Li D, Lowdon R, Elliott G, Mercer TR, Neph SJ, Onuchic V, Polak P, Rajagopal N, Ray P, Sallari RC, Siebenthall KT, Sinnott-Armstrong NA, Stevens M, Thurman RE, Wu J, Zhang B, Zhou X, Beaudet AE, Boyer LA, De Jager PL, Farnham PJ, Fisher SJ, Haussler D, Jones SJ, Li W, Marra MA, McManus MT, Sunyaev S, Thomson JA, Tlsty TD, Tsai LH, Wang W, Waterland RA, Zhang MQ, Chadwick LH, Bernstein BE, Costello JF, Ecker JR, Hirst M, Meissner A, Milosavljevic A, Ren B, Stamatoyannopoulos JA, Wang T, Kellis M. Roadmap Epigenomics Consortium, et al. Among authors: mcmanus mt. Nature. 2015 Feb 19;518(7539):317-30. doi: 10.1038/nature14248. Nature. 2015. PMID: 25693563 Free PMC article.
156 results