McQuade TJ - Search Results

1

Inhibitors of the protease from human immunodeficiency virus: design and modeling of a compound containing a dihydroxyethylene isostere insert with high binding affinity and effective antiviral activity.

Thaisrivongs S, Tomasselli AG, Moon JB, Hui J, McQuade TJ, Turner SR, Strohbach JW, Howe WJ, Tarpley WG, Heinrikson RL. Thaisrivongs S, et al. Among authors: mcquade tj. J Med Chem. 1991 Aug;34(8):2344-56. doi: 10.1021/jm00112a005. J Med Chem. 1991. PMID: 1875334

2

A synthetic HIV-1 protease inhibitor with antiviral activity arrests HIV-like particle maturation.

McQuade TJ, Tomasselli AG, Liu L, Karacostas V, Moss B, Sawyer TK, Heinrikson RL, Tarpley WG. McQuade TJ, et al. Science. 1990 Jan 26;247(4941):454-6. doi: 10.1126/science.2405486. Science. 1990. PMID: 2405486

3

Evaluation of a vitamin-cloaking strategy for oligopeptide therapeutics: biotinylated HIV-1 protease inhibitors.

Islam I, Ng KY, Chong KT, McQuade TJ, Hui JO, Wilkinson KF, Rush BD, Ruwart MJ, Borchardt RT, Fisher JF. Islam I, et al. Among authors: mcquade tj. J Med Chem. 1994 Jan 21;37(2):293-304. doi: 10.1021/jm00028a013. J Med Chem. 1994. PMID: 8295217

4

Inhibitors of the protease from human immunodeficiency virus: synthesis, enzyme inhibition, and antiviral activity of a series of compounds containing the dihydroxyethylene transition-state isostere.

Thaisrivongs S, Turner SR, Strohbach JW, TenBrink RE, Tarpley WG, McQuade TJ, Heinrikson RL, Tomasselli AG, Hui JO, Howe WJ. Thaisrivongs S, et al. Among authors: mcquade tj. J Med Chem. 1993 Apr 16;36(8):941-52. doi: 10.1021/jm00060a001. J Med Chem. 1993. PMID: 8478908

5

Denaturation/refolding of purified recombinant HIV reverse transcriptase yields monomeric enzyme with high enzymatic activity.

Deibel MR Jr, McQuade TJ, Brunner DP, Tarpley WG. Deibel MR Jr, et al. Among authors: mcquade tj. AIDS Res Hum Retroviruses. 1990 Mar;6(3):329-40. doi: 10.1089/aid.1990.6.329. AIDS Res Hum Retroviruses. 1990. PMID: 1692723

6

Metal affinity chromatography of recombinant HIV-1 reverse transcriptase containing a human renin cleavable metal binding domain.

Sharma SK, Evans DB, Vosters AF, McQuade TJ, Tarpley WG. Sharma SK, et al. Among authors: mcquade tj. Biotechnol Appl Biochem. 1991 Aug;14(1):69-81. Biotechnol Appl Biochem. 1991. PMID: 1716913

7

An inhibitor of the protease blocks maturation of human and simian immunodeficiency viruses and spread of infection.

Ashorn P, McQuade TJ, Thaisrivongs S, Tomasselli AG, Tarpley WG, Moss B. Ashorn P, et al. Among authors: mcquade tj. Proc Natl Acad Sci U S A. 1990 Oct;87(19):7472-6. doi: 10.1073/pnas.87.19.7472. Proc Natl Acad Sci U S A. 1990. PMID: 2217178 Free PMC article.

8

A rapid solution immunoassay to quantify binding of the human immunodeficiency virus envelope glycoprotein to soluble CD4.

McQuade TJ, Pitts TW, Tarpley WG. McQuade TJ, et al. Biochem Biophys Res Commun. 1989 Aug 30;163(1):172-6. doi: 10.1016/0006-291x(89)92116-5. Biochem Biophys Res Commun. 1989. PMID: 2549987

9

Purification of an active monomeric recombinant HIV-1 trans-activator.

Waszak GA, Hasler JM, McQuade TJ, Tarpley WG, Deibel MR Jr. Waszak GA, et al. Among authors: mcquade tj. Protein Expr Purif. 1992 Apr;3(2):126-33. Protein Expr Purif. 1992. PMID: 1422216

10

Nonpeptidic potent HIV-1 protease inhibitors: (4-hydroxy-6-phenyl-2-oxo-2H- pyran-3-yl)thiomethanes that span P1-P2' subsites in a unique mode of active site binding.

Prasad JV, Para KS, Tummino PJ, Ferguson D, McQuade TJ, Lunney EA, Rapundalo ST, Batley BL, Hingorani G, Domagala JM, et al. Prasad JV, et al. Among authors: mcquade tj. J Med Chem. 1995 Mar 17;38(6):898-905. doi: 10.1021/jm00006a007. J Med Chem. 1995. PMID: 7699705

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