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The use of mode of action information in risk assessment: quantitative key events/dose-response framework for modeling the dose-response for key events.
Simon TW, Simons SS Jr, Preston RJ, Boobis AR, Cohen SM, Doerrer NG, Fenner-Crisp PA, McMullin TS, McQueen CA, Rowlands JC; RISK21 Dose-Response Subteam. Simon TW, et al. Among authors: mcqueen ca. Crit Rev Toxicol. 2014 Aug;44 Suppl 3:17-43. doi: 10.3109/10408444.2014.931925. Crit Rev Toxicol. 2014. PMID: 25070415 Review.
Dose and Effect Thresholds for Early Key Events in a PPARα-Mediated Mode of Action.
Lake AD, Wood CE, Bhat VS, Chorley BN, Carswell GK, Sey YM, Kenyon EM, Padnos B, Moore TM, Tennant AH, Schmid JE, George BJ, Ross DG, Hughes MF, Corton JC, Simmons JE, McQueen CA, Hester SD. Lake AD, et al. Among authors: mcqueen ca. Toxicol Sci. 2016 Feb;149(2):312-25. doi: 10.1093/toxsci/kfv236. Epub 2015 Oct 31. Toxicol Sci. 2016. PMID: 26519955
The Gut Microbiome and Xenobiotics: Identifying Knowledge Gaps.
Sutherland VL, McQueen CA, Mendrick D, Gulezian D, Cerniglia C, Foley S, Forry S, Khare S, Liang X, Manautou JE, Tweedie D, Young H, Alekseyenko AV, Burns F, Dietert R, Wilson A, Chen C. Sutherland VL, et al. Among authors: mcqueen ca. Toxicol Sci. 2020 Jul 1;176(1):1-10. doi: 10.1093/toxsci/kfaa060. Toxicol Sci. 2020. PMID: 32658296 Free PMC article.
65 results