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Mechanism of calmodulin inactivation of the calcium-selective TRP channel TRPV6.
Singh AK, McGoldrick LL, Twomey EC, Sobolevsky AI. Singh AK, et al. Sci Adv. 2018 Aug 15;4(8):eaau6088. doi: 10.1126/sciadv.aau6088. eCollection 2018 Aug. Sci Adv. 2018. PMID: 30116787 Free PMC article.
Calmodulin (CaM)-mediated Ca(2+)-induced inactivation is an ion channel regulatory mechanism that protects cells against the toxic effects of Ca(2+) overload. We used cryo-electron microscopy to capture the epithelial calcium channel T
Calmodulin (CaM)-mediated Ca(2+)-induced inactivation is an ion channel regulatory mechanism that protects cells
Structure and function of the calcium-selective TRP channel TRPV6.
Yelshanskaya MV, Nadezhdin KD, Kurnikova MG, Sobolevsky AI. Yelshanskaya MV, et al. J Physiol. 2020 Feb 19:10.1113/JP279024. doi: 10.1113/JP279024. Online ahead of print. J Physiol. 2020. PMID: 32073143
Epithelial calcium channel TRPV6 is a member of the vanilloid subfamily of TRP channels that is permeable to cations and highly selective to Ca(2+) ; it shows constitutive activity regulated negatively by Ca(2+) and positively by phosphoi …
Epithelial calcium channel TRPV6 is a member of the vanilloid subfamily of TRP channels that is permeable …
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