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Mechanism of calmodulin inactivation of the calcium-selective TRP channel TRPV6.
Singh AK, McGoldrick LL, Twomey EC, Sobolevsky AI. Singh AK, et al. Sci Adv. 2018 Aug 15;4(8):eaau6088. doi: 10.1126/sciadv.aau6088. eCollection 2018 Aug. Sci Adv. 2018. PMID: 30116787 Free PMC article.
Calmodulin (CaM)-mediated Ca(2+)-induced inactivation is an ion channel regulatory mechanism that protects cells against the toxic effects of Ca(2+) overload. We used cryo-electron microscopy to capture the epithelial calcium channel TRPV6 …
Calmodulin (CaM)-mediated Ca(2+)-induced inactivation is an ion channel regulatory mechanism that protects cells …
Structure and function of the calcium-selective TRP channel TRPV6.
Yelshanskaya MV, Nadezhdin KD, Kurnikova MG, Sobolevsky AI. Yelshanskaya MV, et al. J Physiol. 2021 May;599(10):2673-2697. doi: 10.1113/JP279024. Epub 2020 Mar 13. J Physiol. 2021. PMID: 32073143 Free PMC article. Review.
Epithelial calcium channel TRPV6 is a member of the vanilloid subfamily of TRP channels that is permeable to cations and highly selective to Ca(2+) ; it shows constitutive activity regulated negatively by Ca(2+) and positively by phosphoinositol and ch …
Epithelial calcium channel TRPV6 is a member of the vanilloid subfamily of TRP channels that is permeable to cat …
Calcium selective channel TRPV6: Structure, function, and implications in health and disease.
Khattar V, Wang L, Peng JB. Khattar V, et al. Gene. 2022 Apr 5;817:146192. doi: 10.1016/j.gene.2022.146192. Epub 2022 Jan 11. Gene. 2022. PMID: 35031425 Free PMC article. Review.
Calcium-selective channel TRPV6 (Transient Receptor Potential channel family, Vanilloid subfamily member 6) belongs to the TRP family of cation channels and plays critical roles in transcellular calcium (Ca(2+)) transport, reuptake …
Calcium-selective channel TRPV6 (Transient Receptor Potential channel family, Vanilloid subfamily member …