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Mechanisms of Regulated and Dysregulated CARD11 Signaling in Adaptive Immunity and Disease.
Bedsaul JR, Carter NM, Deibel KE, Hutcherson SM, Jones TA, Wang Z, Yang C, Yang YK, Pomerantz JL. Bedsaul JR, et al. Front Immunol. 2018 Sep 19;9:2105. doi: 10.3389/fimmu.2018.02105. eCollection 2018. Front Immunol. 2018. PMID: 30283447 Free PMC article. Review.
CARD11 functions as a key signaling scaffold that controls antigen-induced lymphocyte activation during the adaptive immune response. ...In this review, we summarize our current understanding of how CARD11 signals, how its activity is regulat
CARD11 functions as a key signaling scaffold that controls antigen-induced lymphocyte activation during the adaptive im
L-CBM signaling in lymphocyte development and function.
Hara H, Iizasa E, Nakaya M, Yoshida H. Hara H, et al. J Blood Med. 2010;1:93-104. doi: 10.2147/JBM.S9772. Epub 2010 Jun 4. J Blood Med. 2010. PMID: 22282688 Free PMC article.
The nuclear factor-kappaB (NF-kappaB) plays a central role in the activation and survival of lymphocytes. NF-kappaB, therefore, is pivotal for acquired immunity, but the dysregulation of NF-kappaB signaling leads to inflammatory diseases and lymphomage …
The nuclear factor-kappaB (NF-kappaB) plays a central role in the activation and survival of lymphocytes. NF-kappaB, therefore, is pivotal f …