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Neuropathology of mood disorders: do we see the stigmata of inflammation?
Mechawar N, Savitz J. Mechawar N, et al. Transl Psychiatry. 2016 Nov 8;6(11):e946. doi: 10.1038/tp.2016.212. Transl Psychiatry. 2016. PMID: 27824355 Free PMC article. Review.
Through the looking glass: examining neuroanatomical evidence for cellular alterations in major depression.
Hercher C, Turecki G, Mechawar N. Hercher C, et al. Among authors: mechawar n. J Psychiatr Res. 2009 Jul;43(11):947-61. doi: 10.1016/j.jpsychires.2009.01.006. Epub 2009 Feb 23. J Psychiatr Res. 2009. PMID: 19233384 Review.
Identification and characterization of spermidine/spermine N1-acetyltransferase promoter variants in suicide completers.
Fiori LM, Mechawar N, Turecki G. Fiori LM, et al. Among authors: mechawar n. Biol Psychiatry. 2009 Sep 1;66(5):460-7. doi: 10.1016/j.biopsych.2009.04.002. Epub 2009 May 15. Biol Psychiatry. 2009. PMID: 19446796
Alcohol dependence-related increase of glial cell density in the anterior cingulate cortex of suicide completers.
Hercher C, Parent M, Flores C, Canetti L, Turecki G, Mechawar N. Hercher C, et al. Among authors: mechawar n. J Psychiatry Neurosci. 2009 Jul;34(4):281-8. J Psychiatry Neurosci. 2009. PMID: 19568479 Free PMC article.
Global brain gene expression analysis links glutamatergic and GABAergic alterations to suicide and major depression.
Sequeira A, Mamdani F, Ernst C, Vawter MP, Bunney WE, Lebel V, Rehal S, Klempan T, Gratton A, Benkelfat C, Rouleau GA, Mechawar N, Turecki G. Sequeira A, et al. Among authors: mechawar n. PLoS One. 2009 Aug 11;4(8):e6585. doi: 10.1371/journal.pone.0006585. PLoS One. 2009. PMID: 19668376 Free PMC article.
Anterior cingulate pyramidal neurons display altered dendritic branching in depressed suicides.
Hercher C, Canetti L, Turecki G, Mechawar N. Hercher C, et al. Among authors: mechawar n. J Psychiatr Res. 2010 Apr;44(5):286-93. doi: 10.1016/j.jpsychires.2009.08.011. Epub 2009 Sep 17. J Psychiatr Res. 2010. PMID: 19765721
To test this hypothesis at the cellular level, we analyzed basilar dendritic arborizations extended by layer VI pyramidal neurons in silver-impregnated postmortem ACC samples from well-characterized depressed suicide subjects (n=12) and matched sudden-death controls (n
To test this hypothesis at the cellular level, we analyzed basilar dendritic arborizations extended by layer VI pyramidal neurons in silver- …
Astrocytic hypertrophy in anterior cingulate white matter of depressed suicides.
Torres-Platas SG, Hercher C, Davoli MA, Maussion G, Labonté B, Turecki G, Mechawar N. Torres-Platas SG, et al. Among authors: mechawar n. Neuropsychopharmacology. 2011 Dec;36(13):2650-8. doi: 10.1038/npp.2011.154. Epub 2011 Aug 3. Neuropsychopharmacology. 2011. PMID: 21814185 Free PMC article.
The neurodevelopmental origins of suicidal behavior.
Turecki G, Ernst C, Jollant F, Labonté B, Mechawar N. Turecki G, et al. Among authors: mechawar n. Trends Neurosci. 2012 Jan;35(1):14-23. doi: 10.1016/j.tins.2011.11.008. Epub 2011 Dec 15. Trends Neurosci. 2012. PMID: 22177979 Review.
Differential glucocorticoid receptor exon 1(B), 1(C), and 1(H) expression and methylation in suicide completers with a history of childhood abuse.
Labonte B, Yerko V, Gross J, Mechawar N, Meaney MJ, Szyf M, Turecki G. Labonte B, et al. Among authors: mechawar n. Biol Psychiatry. 2012 Jul 1;72(1):41-8. doi: 10.1016/j.biopsych.2012.01.034. Epub 2012 Mar 22. Biol Psychiatry. 2012. PMID: 22444201
Amygdalar expression of proteins associated with neuroplasticity in major depression and suicide.
Maheu ME, Davoli MA, Turecki G, Mechawar N. Maheu ME, et al. Among authors: mechawar n. J Psychiatr Res. 2013 Mar;47(3):384-90. doi: 10.1016/j.jpsychires.2012.11.013. Epub 2012 Dec 20. J Psychiatr Res. 2013. PMID: 23260340
METHODS: Basolateral amygdala (BLA) and central amygdala (CeA) postmortem human brain samples were collected from individuals with a history of depression (n = 22 and 25, respectively) and psychiatrically healthy controls (CTRL; n = 14). ...
METHODS: Basolateral amygdala (BLA) and central amygdala (CeA) postmortem human brain samples were collected from individuals with a history …
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