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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1963 1
1964 1
1965 4
1967 4
1968 5
1969 3
1970 6
1971 2
1972 4
1973 2
1974 1
1975 5
1976 2
1977 2
1978 4
1979 3
1980 7
1981 4
1982 2
1983 1
1984 1
1986 3
1987 5
1988 3
1989 5
1990 3
1991 7
1992 5
1993 10
1994 10
1995 7
1996 9
1997 7
1998 7
1999 5
2000 9
2001 8
2002 13
2003 12
2004 10
2005 16
2006 15
2007 21
2008 16
2009 6
2010 8
2011 14
2012 8
2013 6
2014 4
2015 13
2016 11
2017 6
2018 12
2019 13
2020 12
2021 13
2022 14
2023 7

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383 results

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Page 1
Endocannabinoid basis of personality-Insights from animal model of social behavior.
Kogan NM, Begmatova D, Vinnikova L, Malitsky S, Itkin M, Sharon E, Klinov A, Gorelick J, Koman I, Vogel Z, Mechoulam R, Pinhasov A. Kogan NM, et al. Among authors: mechoulam r. Front Pharmacol. 2023 Aug 16;14:1234332. doi: 10.3389/fphar.2023.1234332. eCollection 2023. Front Pharmacol. 2023. PMID: 37663250 Free PMC article.
Behavioral effects induced by the cannabidiol analogs HU-502 and HU-556.
Colodete DAE, Silva NR, Pedrazzi JFC, Fogaça MV, Cortez I, Del-Bel EA, Breuer A, Mechoulam R, Gomes FV, Guimarães FS. Colodete DAE, et al. Among authors: mechoulam r. Behav Pharmacol. 2023 Jun 1;34(4):213-224. doi: 10.1097/FBP.0000000000000727. Epub 2023 May 10. Behav Pharmacol. 2023. PMID: 37171460
Novel Synthesis of C-Methylated Phytocannabinoids Bearing Anti-inflammatory Properties.
Lavi Y, Kogan NM, Topping LM, Liu C, McCann FE, Williams RO, Breuer A, Yekhtin Z, Ezra AF, Gallily R, Feldmann M, Mechoulam R. Lavi Y, et al. Among authors: mechoulam r. J Med Chem. 2023 Apr 27;66(8):5536-5549. doi: 10.1021/acs.jmedchem.2c01988. Epub 2023 Apr 14. J Med Chem. 2023. PMID: 37057997 Free PMC article.
Maintained anxiolytic effects of cannabidiol after treatment discontinuation in healthcare workers during the COVID-19 pandemic.
Souza JDS, Zuardi AW, Guimarães FS, Osório FL, Loureiro SR, Campos AC, Hallak JEC, Dos Santos RG, Machado Silveira IL, Pereira-Lima K, Pacheco JC, Ushirohira JM, Ferreira RR, Costa KCM, Scomparin DS, Scarante FF, Pires-Dos-Santos I, Mechoulam R, Kapczinski F, Fonseca BAL, Esposito DLA, Andraus MH, Crippa JAS. Souza JDS, et al. Among authors: mechoulam r. Front Pharmacol. 2022 Oct 3;13:856846. doi: 10.3389/fphar.2022.856846. eCollection 2022. Front Pharmacol. 2022. PMID: 36263136 Free PMC article.
Cannabidiol for COVID-19 Patients with Mild to Moderate Symptoms (CANDIDATE Study): A Randomized, Double-Blind, Placebo-Controlled Clinical Trial.
Crippa JAS, Pacheco JC, Zuardi AW, Guimarães FS, Campos AC, Osório FL, Loureiro SR, Dos Santos RG, Souza JDS, Ushirohira JM, Ferreira RR, Mancini Costa KC, Scomparin DS, Scarante FF, Pires-Dos-Santos I, Mechoulam R, Kapczinski F, Fonseca BAL, Esposito DLA, Passos ADC, Dal Fabbro AL, Bellissimo-Rodrigues F, Arruda E, Scarpelini S, Andraus MH, Nather Junior JC, Wada DT, Koenigkam-Santos M, Santos AC, Busatto Filho G, Hallak JEC. Crippa JAS, et al. Among authors: mechoulam r. Cannabis Cannabinoid Res. 2022 Oct;7(5):658-669. doi: 10.1089/can.2021.0093. Epub 2021 Oct 7. Cannabis Cannabinoid Res. 2022. PMID: 34619044 Clinical Trial.
Spontaneous and Naloxone-Precipitated Withdrawal Behaviors From Chronic Opiates are Accompanied by Changes in N-Oleoylglycine and N-Oleoylalanine Levels in the Brain and Ameliorated by Treatment With These Mediators.
Ayoub SM, Piscitelli F, Silvestri C, Limebeer CL, Rock EM, Smoum R, Farag M, de Almeida H, Sullivan MT, Lacroix S, Boubertakh B, Nallabelli N, Lichtman AH, Leri F, Mechoulam R, Di Marzo V, Parker LA. Ayoub SM, et al. Among authors: mechoulam r. Front Pharmacol. 2021 Sep 15;12:706703. doi: 10.3389/fphar.2021.706703. eCollection 2021. Front Pharmacol. 2021. PMID: 34603019 Free PMC article.
Novel CBG Derivatives Can Reduce Inflammation, Pain and Obesity.
Kogan NM, Lavi Y, Topping LM, Williams RO, McCann FE, Yekhtin Z, Feldmann M, Gallily R, Mechoulam R. Kogan NM, et al. Among authors: mechoulam r. Molecules. 2021 Sep 15;26(18):5601. doi: 10.3390/molecules26185601. Molecules. 2021. PMID: 34577072 Free PMC article.
Efficacy and Safety of Cannabidiol Plus Standard Care vs Standard Care Alone for the Treatment of Emotional Exhaustion and Burnout Among Frontline Health Care Workers During the COVID-19 Pandemic: A Randomized Clinical Trial.
Crippa JAS, Zuardi AW, Guimarães FS, Campos AC, de Lima Osório F, Loureiro SR, Dos Santos RG, Souza JDS, Ushirohira JM, Pacheco JC, Ferreira RR, Mancini Costa KC, Scomparin DS, Scarante FF, Pires-Dos-Santos I, Mechoulam R, Kapczinski F, Fonseca BAL, Esposito DLA, Pereira-Lima K, Sen S, Andraus MH, Hallak JEC; Burnout and Distress Prevention With Cannabidiol in Front-line Health Care Workers Dealing With COVID-19 (BONSAI) Trial Investigators. Crippa JAS, et al. Among authors: mechoulam r. JAMA Netw Open. 2021 Aug 2;4(8):e2120603. doi: 10.1001/jamanetworkopen.2021.20603. JAMA Netw Open. 2021. PMID: 34387679 Free PMC article.
Assessing the treatment of cannabidiolic acid methyl ester: a stable synthetic analogue of cannabidiolic acid on c-Fos and NeuN expression in the hypothalamus of rats.
Murillo-Rodríguez E, Millán-Aldaco D, Arankowsky-Sandoval G, Yamamoto T, Pertwee RG, Parker L, Mechoulam R. Murillo-Rodríguez E, et al. Among authors: mechoulam r. J Cannabis Res. 2021 Jul 12;3(1):31. doi: 10.1186/s42238-021-00081-1. J Cannabis Res. 2021. PMID: 34253253 Free PMC article.
Cannabinoid Quinones-A Review and Novel Observations.
Kogan NM, Peters M, Mechoulam R. Kogan NM, et al. Among authors: mechoulam r. Molecules. 2021 Mar 21;26(6):1761. doi: 10.3390/molecules26061761. Molecules. 2021. PMID: 33801057 Free PMC article. Review.
Anti-Biofilm Activity of Cannabidiol against Candida albicans.
Feldman M, Sionov RV, Mechoulam R, Steinberg D. Feldman M, et al. Among authors: mechoulam r. Microorganisms. 2021 Feb 20;9(2):441. doi: 10.3390/microorganisms9020441. Microorganisms. 2021. PMID: 33672633 Free PMC article.
Crosstalk between the transcriptional regulation of dopamine D2 and cannabinoid CB1 receptors in schizophrenia: Analyses in patients and in perinatal Δ9-tetrahydrocannabinol-exposed rats.
Di Bartolomeo M, Stark T, Maurel OM, Iannotti FA, Kuchar M, Ruda-Kucerova J, Piscitelli F, Laudani S, Pekarik V, Salomone S, Arosio B, Mechoulam R, Maccarrone M, Drago F, Wotjak CT, Di Marzo V, Vismara M, Dell'Osso B, D'Addario C, Micale V. Di Bartolomeo M, et al. Among authors: mechoulam r. Pharmacol Res. 2021 Feb;164:105357. doi: 10.1016/j.phrs.2020.105357. Epub 2020 Dec 4. Pharmacol Res. 2021. PMID: 33285233 Free article.
Oleoyl alanine (HU595): a stable monomethylated oleoyl glycine interferes with acute naloxone precipitated morphine withdrawal in male rats.
Ayoub SM, Smoum R, Farag M, Atwal H, Collins SA, Rock EM, Limebeer CL, Piscitelli F, Iannotti FA, Lichtman AH, Leri F, Di Marzo V, Mechoulam R, Parker LA. Ayoub SM, et al. Among authors: mechoulam r. Psychopharmacology (Berl). 2020 Sep;237(9):2753-2765. doi: 10.1007/s00213-020-05570-4. Epub 2020 Jun 16. Psychopharmacology (Berl). 2020. PMID: 32556401
Altered dopamine D3 receptor gene expression in MAM model of schizophrenia is reversed by peripubertal cannabidiol treatment.
Stark T, Di Bartolomeo M, Di Marco R, Drazanova E, Platania CBM, Iannotti FA, Ruda-Kucerova J, D'Addario C, Kratka L, Pekarik V, Piscitelli F, Babinska Z, Fedotova J, Giurdanella G, Salomone S, Sulcova A, Bucolo C, Wotjak CT, Starcuk Z Jr, Drago F, Mechoulam R, Di Marzo V, Micale V. Stark T, et al. Among authors: mechoulam r. Biochem Pharmacol. 2020 Jul;177:114004. doi: 10.1016/j.bcp.2020.114004. Epub 2020 Apr 28. Biochem Pharmacol. 2020. PMID: 32360362
Protective Effects of N-Oleoylglycine in a Mouse Model of Mild Traumatic Brain Injury.
Piscitelli F, Guida F, Luongo L, Iannotti FA, Boccella S, Verde R, Lauritano A, Imperatore R, Smoum R, Cristino L, Lichtman AH, Parker LA, Mechoulam R, Maione S, Di Marzo V. Piscitelli F, et al. Among authors: mechoulam r. ACS Chem Neurosci. 2020 Apr 15;11(8):1117-1128. doi: 10.1021/acschemneuro.9b00633. Epub 2020 Apr 2. ACS Chem Neurosci. 2020. PMID: 32017529
Beyond THC and Endocannabinoids.
Pacher P, Kogan NM, Mechoulam R. Pacher P, et al. Among authors: mechoulam r. Annu Rev Pharmacol Toxicol. 2020 Jan 6;60:637-659. doi: 10.1146/annurev-pharmtox-010818-021441. Epub 2019 Oct 3. Annu Rev Pharmacol Toxicol. 2020. PMID: 31580774 Review.
Oleoyl glycine: interference with the aversive effects of acute naloxone-precipitated MWD, but not morphine reward, in male Sprague-Dawley rats.
Petrie GN, Wills KL, Piscitelli F, Smoum R, Limebeer CL, Rock EM, Humphrey AE, Sheppard-Perkins M, Lichtman AH, Mechoulam R, Di Marzo V, Parker LA. Petrie GN, et al. Among authors: mechoulam r. Psychopharmacology (Berl). 2019 Sep;236(9):2623-2633. doi: 10.1007/s00213-019-05237-9. Epub 2019 Apr 16. Psychopharmacology (Berl). 2019. PMID: 30993360
Peripubertal cannabidiol treatment rescues behavioral and neurochemical abnormalities in the MAM model of schizophrenia.
Stark T, Ruda-Kucerova J, Iannotti FA, D'Addario C, Di Marco R, Pekarik V, Drazanova E, Piscitelli F, Bari M, Babinska Z, Giurdanella G, Di Bartolomeo M, Salomone S, Sulcova A, Maccarrone M, Wotjak CT, Starcuk Z Jr, Drago F, Mechoulam R, Di Marzo V, Micale V. Stark T, et al. Among authors: mechoulam r. Neuropharmacology. 2019 Mar 1;146:212-221. doi: 10.1016/j.neuropharm.2018.11.035. Epub 2018 Nov 26. Neuropharmacology. 2019. PMID: 30496751
Role of CB2 Receptor in the Recovery of Mice after Traumatic Brain Injury.
Magid L, Heymann S, Elgali M, Avram L, Cohen Y, Liraz-Zaltsman S, Mechoulam R, Shohami E. Magid L, et al. Among authors: mechoulam r. J Neurotrauma. 2019 Jun;36(11):1836-1846. doi: 10.1089/neu.2018.6063. Epub 2019 Feb 7. J Neurotrauma. 2019. PMID: 30489198 Free PMC article.
Magel2 Modulates Bone Remodeling and Mass in Prader-Willi Syndrome by Affecting Oleoyl Serine Levels and Activity.
Baraghithy S, Smoum R, Drori A, Hadar R, Gammal A, Hirsch S, Attar-Namdar M, Nemirovski A, Gabet Y, Langer Y, Pollak Y, Schaaf CP, Rech ME, Gross-Tsur V, Bab I, Mechoulam R, Tam J. Baraghithy S, et al. Among authors: mechoulam r. J Bone Miner Res. 2019 Jan;34(1):93-105. doi: 10.1002/jbmr.3591. Epub 2018 Oct 22. J Bone Miner Res. 2019. PMID: 30347474 Free article.
N-Oleoyl-glycine reduces nicotine reward and withdrawal in mice.
Donvito G, Piscitelli F, Muldoon P, Jackson A, Vitale RM, D'Aniello E, Giordano C, Ignatowska-Jankowska BM, Mustafa MA, Guida F, Petrie GN, Parker L, Smoum R, Sim-Selley L, Maione S, Lichtman AH, Damaj MI, Di Marzo V, Mechoulam R. Donvito G, et al. Among authors: mechoulam r. Neuropharmacology. 2019 Apr;148:320-331. doi: 10.1016/j.neuropharm.2018.03.020. Epub 2018 Mar 19. Neuropharmacology. 2019. PMID: 29567093 Free PMC article.
Antinociceptive effects of HUF-101, a fluorinated cannabidiol derivative.
Silva NR, Gomes FV, Fonseca MD, Mechoulam R, Breuer A, Cunha TM, Guimarães FS. Silva NR, et al. Among authors: mechoulam r. Prog Neuropsychopharmacol Biol Psychiatry. 2017 Oct 3;79(Pt B):369-377. doi: 10.1016/j.pnpbp.2017.07.012. Epub 2017 Jul 15. Prog Neuropsychopharmacol Biol Psychiatry. 2017. PMID: 28720466
HDAC1 and HDAC3 underlie dynamic H3K9 acetylation during embryonic neurogenesis and in schizophrenia-like animals.
Večeřa J, Bártová E, Krejčí J, Legartová S, Komůrková D, Rudá-Kučerová J, Štark T, Dražanová E, Kašpárek T, Šulcová A, Dekker FJ, Szymanski W, Seiser C, Weitzer G, Mechoulam R, Micale V, Kozubek S. Večeřa J, et al. Among authors: mechoulam r. J Cell Physiol. 2018 Jan;233(1):530-548. doi: 10.1002/jcp.25914. Epub 2017 May 3. J Cell Physiol. 2018. PMID: 28300292
Cannabis and epilepsy.
Mechoulam R. Mechoulam R. Epilepsy Behav. 2017 May;70(Pt B):278-279. doi: 10.1016/j.yebeh.2017.01.014. Epub 2017 Feb 21. Epilepsy Behav. 2017. PMID: 28254349 No abstract available.
Correction: Fluorinated Cannabidiol Derivatives: Enhancement of Activity in Mice Models Predictive of Anxiolytic, Antidepressant and Antipsychotic Effects.
Breuer A, Haj CG, Fogaça MV, Gomes FV, Silva NR, Pedrazzi JF, Del Bel EA, Hallak JC, Crippa JA, Zuardi AW, Mechoulam R, Guimarães FS. Breuer A, et al. Among authors: mechoulam r. PLoS One. 2016 Aug 25;11(8):e0162087. doi: 10.1371/journal.pone.0162087. eCollection 2016. PLoS One. 2016. PMID: 27560809 Free PMC article.
Fluorinated Cannabidiol Derivatives: Enhancement of Activity in Mice Models Predictive of Anxiolytic, Antidepressant and Antipsychotic Effects.
Breuer A, Haj CG, Fogaça MV, Gomes FV, Silva NR, Pedrazzi JF, Del Bel EA, Hallak JC, Crippa JA, Zuardi AW, Mechoulam R, Guimarães FS. Breuer A, et al. Among authors: mechoulam r. PLoS One. 2016 Jul 14;11(7):e0158779. doi: 10.1371/journal.pone.0158779. eCollection 2016. PLoS One. 2016. PMID: 27416026 Free PMC article.
In vitro and in vivo efficacy of non-psychoactive cannabidiol in neuroblastoma.
Fisher T, Golan H, Schiby G, PriChen S, Smoum R, Moshe I, Peshes-Yaloz N, Castiel A, Waldman D, Gallily R, Mechoulam R, Toren A. Fisher T, et al. Among authors: mechoulam r. Curr Oncol. 2016 Mar;23(2):S15-22. doi: 10.3747/co.23.2893. Epub 2016 Mar 16. Curr Oncol. 2016. PMID: 27022310 Free PMC article.
Prohedonic Effect of Cannabidiol in a Rat Model of Depression.
Shoval G, Shbiro L, Hershkovitz L, Hazut N, Zalsman G, Mechoulam R, Weller A. Shoval G, et al. Among authors: mechoulam r. Neuropsychobiology. 2016;73(2):123-9. doi: 10.1159/000443890. Epub 2016 Mar 25. Neuropsychobiology. 2016. PMID: 27010632
Cannabis - the Israeli perspective.
Mechoulam R. Mechoulam R. J Basic Clin Physiol Pharmacol. 2016 May 1;27(3):181-7. doi: 10.1515/jbcpp-2015-0091. J Basic Clin Physiol Pharmacol. 2016. PMID: 26426888 Free article. Review.
HU-444, a Novel, Potent Anti-Inflammatory, Nonpsychotropic Cannabinoid.
Haj CG, Sumariwalla PF, Hanuš L, Kogan NM, Yektin Z, Mechoulam R, Feldmann M, Gallily R. Haj CG, et al. Among authors: mechoulam r. J Pharmacol Exp Ther. 2015 Oct;355(1):66-75. doi: 10.1124/jpet.115.226100. Epub 2015 Aug 13. J Pharmacol Exp Ther. 2015. PMID: 26272937 Free PMC article.
CB2 cannabinoid receptor agonist enantiomers HU-433 and HU-308: An inverse relationship between binding affinity and biological potency.
Smoum R, Baraghithy S, Chourasia M, Breuer A, Mussai N, Attar-Namdar M, Kogan NM, Raphael B, Bolognini D, Cascio MG, Marini P, Pertwee RG, Shurki A, Mechoulam R, Bab I. Smoum R, et al. Among authors: mechoulam r. Proc Natl Acad Sci U S A. 2015 Jul 14;112(28):8774-9. doi: 10.1073/pnas.1503395112. Epub 2015 Jun 29. Proc Natl Acad Sci U S A. 2015. PMID: 26124120 Free PMC article.
Cannabidiol for the Prevention of Graft-versus-Host-Disease after Allogeneic Hematopoietic Cell Transplantation: Results of a Phase II Study.
Yeshurun M, Shpilberg O, Herscovici C, Shargian L, Dreyer J, Peck A, Israeli M, Levy-Assaraf M, Gruenewald T, Mechoulam R, Raanani P, Ram R. Yeshurun M, et al. Among authors: mechoulam r. Biol Blood Marrow Transplant. 2015 Oct;21(10):1770-5. doi: 10.1016/j.bbmt.2015.05.018. Epub 2015 May 30. Biol Blood Marrow Transplant. 2015. PMID: 26033282 Free article. Clinical Trial.
Cannabidiol, a Major Non-Psychotropic Cannabis Constituent Enhances Fracture Healing and Stimulates Lysyl Hydroxylase Activity in Osteoblasts.
Kogan NM, Melamed E, Wasserman E, Raphael B, Breuer A, Stok KS, Sondergaard R, Escudero AV, Baraghithy S, Attar-Namdar M, Friedlander-Barenboim S, Mathavan N, Isaksson H, Mechoulam R, Müller R, Bajayo A, Gabet Y, Bab I. Kogan NM, et al. Among authors: mechoulam r. J Bone Miner Res. 2015 Oct;30(10):1905-13. doi: 10.1002/jbmr.2513. Epub 2015 May 10. J Bone Miner Res. 2015. PMID: 25801536 Free article.
Endocannabinoid signaling at the periphery: 50 years after THC.
Maccarrone M, Bab I, Bíró T, Cabral GA, Dey SK, Di Marzo V, Konje JC, Kunos G, Mechoulam R, Pacher P, Sharkey KA, Zimmer A. Maccarrone M, et al. Among authors: mechoulam r. Trends Pharmacol Sci. 2015 May;36(5):277-96. doi: 10.1016/j.tips.2015.02.008. Epub 2015 Mar 18. Trends Pharmacol Sci. 2015. PMID: 25796370 Free PMC article. Review.
Towards a better cannabis drug.
Mechoulam R, Parker L. Mechoulam R, et al. Br J Pharmacol. 2013 Dec;170(7):1363-4. doi: 10.1111/bph.12400. Br J Pharmacol. 2013. PMID: 24024867 Free PMC article.
The endocannabinoid system and the brain.
Mechoulam R, Parker LA. Mechoulam R, et al. Annu Rev Psychol. 2013;64:21-47. doi: 10.1146/annurev-psych-113011-143739. Epub 2012 Jul 12. Annu Rev Psychol. 2013. PMID: 22804774 Review.
Cannabidiol, a non-psychotropic component of cannabis, attenuates vomiting and nausea-like behaviour via indirect agonism of 5-HT(1A) somatodendritic autoreceptors in the dorsal raphe nucleus.
Rock EM, Bolognini D, Limebeer CL, Cascio MG, Anavi-Goffer S, Fletcher PJ, Mechoulam R, Pertwee RG, Parker LA. Rock EM, et al. Among authors: mechoulam r. Br J Pharmacol. 2012 Apr;165(8):2620-34. doi: 10.1111/j.1476-5381.2011.01621.x. Br J Pharmacol. 2012. PMID: 21827451 Free PMC article.
Prospects for cannabinoid therapies in basal ganglia disorders.
Fernández-Ruiz J, Moreno-Martet M, Rodríguez-Cueto C, Palomo-Garo C, Gómez-Cañas M, Valdeolivas S, Guaza C, Romero J, Guzmán M, Mechoulam R, Ramos JA. Fernández-Ruiz J, et al. Among authors: mechoulam r. Br J Pharmacol. 2011 Aug;163(7):1365-78. doi: 10.1111/j.1476-5381.2011.01365.x. Br J Pharmacol. 2011. PMID: 21545415 Free PMC article. Review.
A new cannabinoid CB2 receptor agonist HU-910 attenuates oxidative stress, inflammation and cell death associated with hepatic ischaemia/reperfusion injury.
Horváth B, Magid L, Mukhopadhyay P, Bátkai S, Rajesh M, Park O, Tanchian G, Gao RY, Goodfellow CE, Glass M, Mechoulam R, Pacher P. Horváth B, et al. Among authors: mechoulam r. Br J Pharmacol. 2012 Apr;165(8):2462-78. doi: 10.1111/j.1476-5381.2011.01381.x. Br J Pharmacol. 2012. PMID: 21449982 Free PMC article.
Endocannabinoids and traumatic brain injury.
Shohami E, Cohen-Yeshurun A, Magid L, Algali M, Mechoulam R. Shohami E, et al. Among authors: mechoulam r. Br J Pharmacol. 2011 Aug;163(7):1402-10. doi: 10.1111/j.1476-5381.2011.01343.x. Br J Pharmacol. 2011. PMID: 21418185 Free PMC article. Review.
Administration of 2-arachidonoylglycerol ameliorates both acute and chronic experimental autoimmune encephalomyelitis.
Lourbopoulos A, Grigoriadis N, Lagoudaki R, Touloumi O, Polyzoidou E, Mavromatis I, Tascos N, Breuer A, Ovadia H, Karussis D, Shohami E, Mechoulam R, Simeonidou C. Lourbopoulos A, et al. Among authors: mechoulam r. Brain Res. 2011 May 16;1390:126-41. doi: 10.1016/j.brainres.2011.03.020. Epub 2011 Mar 13. Brain Res. 2011. PMID: 21406188
Cannabidiol protects against hepatic ischemia/reperfusion injury by attenuating inflammatory signaling and response, oxidative/nitrative stress, and cell death.
Mukhopadhyay P, Rajesh M, Horváth B, Bátkai S, Park O, Tanchian G, Gao RY, Patel V, Wink DA, Liaudet L, Haskó G, Mechoulam R, Pacher P. Mukhopadhyay P, et al. Among authors: mechoulam r. Free Radic Biol Med. 2011 May 15;50(10):1368-81. doi: 10.1016/j.freeradbiomed.2011.02.021. Epub 2011 Mar 11. Free Radic Biol Med. 2011. PMID: 21362471 Free PMC article.
Cannabidiol attenuates cardiac dysfunction, oxidative stress, fibrosis, and inflammatory and cell death signaling pathways in diabetic cardiomyopathy.
Rajesh M, Mukhopadhyay P, Bátkai S, Patel V, Saito K, Matsumoto S, Kashiwaya Y, Horváth B, Mukhopadhyay B, Becker L, Haskó G, Liaudet L, Wink DA, Veves A, Mechoulam R, Pacher P. Rajesh M, et al. Among authors: mechoulam r. J Am Coll Cardiol. 2010 Dec 14;56(25):2115-25. doi: 10.1016/j.jacc.2010.07.033. J Am Coll Cardiol. 2010. PMID: 21144973 Free PMC article.
Oleoyl serine, an endogenous N-acyl amide, modulates bone remodeling and mass.
Smoum R, Bar A, Tan B, Milman G, Attar-Namdar M, Ofek O, Stuart JM, Bajayo A, Tam J, Kram V, O'Dell D, Walker MJ, Bradshaw HB, Bab I, Mechoulam R. Smoum R, et al. Among authors: mechoulam r. Proc Natl Acad Sci U S A. 2010 Oct 12;107(41):17710-5. doi: 10.1073/pnas.0912479107. Epub 2010 Sep 27. Proc Natl Acad Sci U S A. 2010. PMID: 20876113 Free PMC article.
Endocannabinoid signaling in neurotoxicity and neuroprotection.
Pope C, Mechoulam R, Parsons L. Pope C, et al. Among authors: mechoulam r. Neurotoxicology. 2010 Sep;31(5):562-71. doi: 10.1016/j.neuro.2009.12.002. Epub 2009 Dec 5. Neurotoxicology. 2010. PMID: 19969019 Free PMC article.
A study investigating the acute dose-response effects of 13 mg and 17 mg Delta 9- tetrahydrocannabinol on cognitive-motor skills, subjective and autonomic measures in regular users of marijuana.
Weinstein A, Brickner O, Lerman H, Greemland M, Bloch M, Lester H, Chisin R, Sarne Y, Mechoulam R, Bar-Hamburger R, Freedman N, Even-Sapir E. Weinstein A, et al. Among authors: mechoulam r. J Psychopharmacol. 2008 Jun;22(4):441-51. doi: 10.1177/0269881108088194. J Psychopharmacol. 2008. PMID: 18635724 Clinical Trial.
Incensole acetate: a novel neuroprotective agent isolated from Boswellia carterii.
Moussaieff A, Shein NA, Tsenter J, Grigoriadis S, Simeonidou C, Alexandrovich AG, Trembovler V, Ben-Neriah Y, Schmitz ML, Fiebich BL, Munoz E, Mechoulam R, Shohami E. Moussaieff A, et al. Among authors: mechoulam r. J Cereb Blood Flow Metab. 2008 Jul;28(7):1341-52. doi: 10.1038/jcbfm.2008.28. Epub 2008 Apr 16. J Cereb Blood Flow Metab. 2008. PMID: 18414499
The CB(2) cannabinoid receptor controls myeloid progenitor trafficking: involvement in the pathogenesis of an animal model of multiple sclerosis.
Palazuelos J, Davoust N, Julien B, Hatterer E, Aguado T, Mechoulam R, Benito C, Romero J, Silva A, Guzmán M, Nataf S, Galve-Roperh I. Palazuelos J, et al. Among authors: mechoulam r. J Biol Chem. 2008 May 9;283(19):13320-9. doi: 10.1074/jbc.M707960200. Epub 2008 Mar 11. J Biol Chem. 2008. PMID: 18334483 Free article.
Cannabinoids in health and disease.
Kogan NM, Mechoulam R. Kogan NM, et al. Among authors: mechoulam r. Dialogues Clin Neurosci. 2007;9(4):413-30. doi: 10.31887/DCNS.2007.9.4/nkogan. Dialogues Clin Neurosci. 2007. PMID: 18286801 Free PMC article. Review.
Presence of functional cannabinoid receptors in human endocrine pancreas.
Bermúdez-Silva FJ, Suárez J, Baixeras E, Cobo N, Bautista D, Cuesta-Muñoz AL, Fuentes E, Juan-Pico P, Castro MJ, Milman G, Mechoulam R, Nadal A, Rodríguez de Fonseca F. Bermúdez-Silva FJ, et al. Among authors: mechoulam r. Diabetologia. 2008 Mar;51(3):476-87. doi: 10.1007/s00125-007-0890-y. Epub 2007 Dec 19. Diabetologia. 2008. PMID: 18092149
Endocannabinoids and traumatic brain injury.
Mechoulam R, Shohami E. Mechoulam R, et al. Mol Neurobiol. 2007 Aug;36(1):68-74. doi: 10.1007/s12035-007-8008-6. Epub 2007 Sep 18. Mol Neurobiol. 2007. PMID: 17952651 Review.
Brain imaging study of the acute effects of Delta9-tetrahydrocannabinol (THC) on attention and motor coordination in regular users of marijuana.
Weinstein A, Brickner O, Lerman H, Greemland M, Bloch M, Lester H, Chisin R, Mechoulam R, Bar-Hamburger R, Freedman N, Even-Sapir E. Weinstein A, et al. Among authors: mechoulam r. Psychopharmacology (Berl). 2008 Jan;196(1):119-31. doi: 10.1007/s00213-007-0940-7. Epub 2007 Sep 26. Psychopharmacology (Berl). 2008. PMID: 17899017
Cannabidiol arrests onset of autoimmune diabetes in NOD mice.
Weiss L, Zeira M, Reich S, Slavin S, Raz I, Mechoulam R, Gallily R. Weiss L, et al. Among authors: mechoulam r. Neuropharmacology. 2008 Jan;54(1):244-9. doi: 10.1016/j.neuropharm.2007.06.029. Epub 2007 Jul 17. Neuropharmacology. 2008. PMID: 17714746 Free PMC article.
Cannabidiol--recent advances.
Mechoulam R, Peters M, Murillo-Rodriguez E, Hanus LO. Mechoulam R, et al. Chem Biodivers. 2007 Aug;4(8):1678-92. doi: 10.1002/cbdv.200790147. Chem Biodivers. 2007. PMID: 17712814 Review.
The cannabinoid CB1 receptor regulates bone formation by modulating adrenergic signaling.
Tam J, Trembovler V, Di Marzo V, Petrosino S, Leo G, Alexandrovich A, Regev E, Casap N, Shteyer A, Ledent C, Karsak M, Zimmer A, Mechoulam R, Yirmiya R, Shohami E, Bab I. Tam J, et al. Among authors: mechoulam r. FASEB J. 2008 Jan;22(1):285-94. doi: 10.1096/fj.06-7957com. Epub 2007 Aug 17. FASEB J. 2008. PMID: 17704191
PADMA-28, a traditional tibetan herbal preparation inhibits the respiratory burst in human neutrophils, the killing of epithelial cells by mixtures of oxidants and pro-inflammatory agonists and peroxidation of lipids.
Ginsburg I, Sadovnik M, Sallon S, Milo-Goldzweig I, Mechoulam R, Breuer A, Gibbs D, Varani J, Roberts S, Cleator E, Singh N. Ginsburg I, et al. Among authors: mechoulam r. Inflammopharmacology. 1999;7(1):47-62. doi: 10.1007/s10787-999-0025-9. Inflammopharmacology. 1999. PMID: 17657446
Attenuation of allergic contact dermatitis through the endocannabinoid system.
Karsak M, Gaffal E, Date R, Wang-Eckhardt L, Rehnelt J, Petrosino S, Starowicz K, Steuder R, Schlicker E, Cravatt B, Mechoulam R, Buettner R, Werner S, Di Marzo V, Tüting T, Zimmer A. Karsak M, et al. Among authors: mechoulam r. Science. 2007 Jun 8;316(5830):1494-7. doi: 10.1126/science.1142265. Science. 2007. PMID: 17556587
Conversation with Raphael Mechoulam.
Mechoulam R. Mechoulam R. Addiction. 2007 Jun;102(6):887-93. doi: 10.1111/j.1360-0443.2007.01795.x. Addiction. 2007. PMID: 17523982 No abstract available.
Endothelial-mediated regulation of cerebral microcirculation.
McCarron RM, Chen Y, Tomori T, Strasser A, Mechoulam R, Shohami E, Spatz M. McCarron RM, et al. Among authors: mechoulam r. J Physiol Pharmacol. 2006 Nov;57 Suppl 11:133-44. J Physiol Pharmacol. 2006. PMID: 17244945
Cannabidiol, a constituent of Cannabis sativa, modulates sleep in rats.
Murillo-Rodríguez E, Millán-Aldaco D, Palomero-Rivero M, Mechoulam R, Drucker-Colín R. Murillo-Rodríguez E, et al. Among authors: mechoulam r. FEBS Lett. 2006 Aug 7;580(18):4337-45. doi: 10.1016/j.febslet.2006.04.102. Epub 2006 Jul 10. FEBS Lett. 2006. PMID: 16844117 Free article.
The chemistry of endocannabinoids.
Kogan NM, Mechoulam R. Kogan NM, et al. Among authors: mechoulam r. J Endocrinol Invest. 2006;29(3 Suppl):3-14. J Endocrinol Invest. 2006. PMID: 16751705 Review.
Multiple sclerosis may disrupt endocannabinoid brain protection mechanism.
Shohami E, Mechoulam R. Shohami E, et al. Among authors: mechoulam r. Proc Natl Acad Sci U S A. 2006 Apr 18;103(16):6087-8. doi: 10.1073/pnas.0601847103. Epub 2006 Apr 10. Proc Natl Acad Sci U S A. 2006. PMID: 16606822 Free PMC article. No abstract available.
Peripheral cannabinoid receptor, CB2, regulates bone mass.
Ofek O, Karsak M, Leclerc N, Fogel M, Frenkel B, Wright K, Tam J, Attar-Namdar M, Kram V, Shohami E, Mechoulam R, Zimmer A, Bab I. Ofek O, et al. Among authors: mechoulam r. Proc Natl Acad Sci U S A. 2006 Jan 17;103(3):696-701. doi: 10.1073/pnas.0504187103. Epub 2006 Jan 9. Proc Natl Acad Sci U S A. 2006. PMID: 16407142 Free PMC article.
Cannabinoids: between neuroprotection and neurotoxicity.
Sarne Y, Mechoulam R. Sarne Y, et al. Among authors: mechoulam r. Curr Drug Targets CNS Neurol Disord. 2005 Dec;4(6):677-84. doi: 10.2174/156800705774933005. Curr Drug Targets CNS Neurol Disord. 2005. PMID: 16375685 Review.
Toward an anandamide transporter.
Mechoulam R, Deutsch DG. Mechoulam R, et al. Proc Natl Acad Sci U S A. 2005 Dec 6;102(49):17541-2. doi: 10.1073/pnas.0508644102. Epub 2005 Nov 28. Proc Natl Acad Sci U S A. 2005. PMID: 16314567 Free PMC article. No abstract available.
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