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Regulation of chromatin structure by site-specific histone H3 methyltransferases.
Rea S, Eisenhaber F, O'Carroll D, Strahl BD, Sun ZW, Schmid M, Opravil S, Mechtler K, Ponting CP, Allis CD, Jenuwein T. Rea S, et al. Nature. 2000 Aug 10;406(6796):593-9. doi: 10.1038/35020506. Nature. 2000. PMID: 10949293
Methylation of histone H3 lysine 9 creates a binding site for HP1 proteins.
Lachner M, O'Carroll D, Rea S, Mechtler K, Jenuwein T. Lachner M, et al. Nature. 2001 Mar 1;410(6824):116-20. doi: 10.1038/35065132. Nature. 2001. PMID: 11242053
Dissociation of cohesin from chromosome arms and loss of arm cohesion during early mitosis depends on phosphorylation of SA2.
Hauf S, Roitinger E, Koch B, Dittrich CM, Mechtler K, Peters JM. Hauf S, et al. PLoS Biol. 2005 Mar;3(3):e69. doi: 10.1371/journal.pbio.0030069. Epub 2005 Mar 1. PLoS Biol. 2005. PMID: 15737063 Free PMC article.
Protein phosphatase 2A protects centromeric sister chromatid cohesion during meiosis I.
Riedel CG, Katis VL, Katou Y, Mori S, Itoh T, Helmhart W, Gálová M, Petronczki M, Gregan J, Cetin B, Mudrak I, Ogris E, Mechtler K, Pelletier L, Buchholz F, Shirahige K, Nasmyth K. Riedel CG, et al. Nature. 2006 May 4;441(7089):53-61. doi: 10.1038/nature04664. Epub 2006 Mar 15. Nature. 2006. PMID: 16541024
Isotope-labeled cross-linkers and Fourier transform ion cyclotron resonance mass spectrometry for structural analysis of a protein/peptide complex.
Ihling C, Schmidt A, Kalkhof S, Schulz DM, Stingl C, Mechtler K, Haack M, Beck-Sickinger AG, Cooper DMF, Sinz A. Ihling C, et al. J Am Soc Mass Spectrom. 2006 Aug;17(8):1100-1113. doi: 10.1016/j.jasms.2006.04.020. Epub 2006 Jun 5. J Am Soc Mass Spectrom. 2006. PMID: 16750914
Cleaning of raw peptide MS/MS spectra: improved protein identification following deconvolution of multiply charged peaks, isotope clusters, and removal of background noise.
Mujezinovic N, Raidl G, Hutchins JR, Peters JM, Mechtler K, Eisenhaber F. Mujezinovic N, et al. Proteomics. 2006 Oct;6(19):5117-31. doi: 10.1002/pmic.200500928. Proteomics. 2006. PMID: 16955515
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