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Medical Plants and Nutraceuticals for Amyloid-beta Fibrillation Inhibition.
Witter S, Witter R, Vilu R, Samoson A. Witter S, et al. J Alzheimers Dis Rep. 2018 Dec 24;2(1):239-252. doi: 10.3233/ADR-180066. J Alzheimers Dis Rep. 2018. PMID: 30599045 Free PMC article.
Plaque formation due to amyloid-beta oligomerization and fibrillation is a key issue for its deposition in the brains of dementia and Alzheimer's disease patients. ...In this study, we performed in vitro fibrillation inhibition tests with …
Plaque formation due to amyloid-beta oligomerization and fibrillation is a key issue for its deposition in the brains o …
Screening of Nutraceuticals and Plant Extracts for Inhibition of Amyloid-beta Fibrillation.
Witter S, Samoson A, Vilu R, Witter R. Witter S, et al. J Alzheimers Dis. 2020;73(3):1003-1012. doi: 10.3233/JAD-190758. J Alzheimers Dis. 2020. PMID: 31884466
Fluorescence spectroscopy for in vitro amyloid-beta (Abeta) fibrillation diagnosis and spectral fluorescence signature for the identification of bioactive compounds were applied to study traditional Ayurvedic nutraceuticals - Brahmi, Ashwagandha, Shank …
Fluorescence spectroscopy for in vitro amyloid-beta (Abeta) fibrillation diagnosis and spectral fluorescence signature …
Prospects of Saffron and its Derivatives in Alzheimer's Disease.
Zandi N, Pazoki B, Momeni Roudsari N, Lashgari NA, Jamshidi V, Momtaz S, Abdolghaffari AH, Akhondzadeh S. Zandi N, et al. Arch Iran Med. 2021 Mar 1;24(3):233-252. doi: 10.34172/aim.2021.35. Arch Iran Med. 2021. PMID: 33878882 Review.
Accumulating evidence supports the beneficial roles of natural-based products in brain function, neurotransmission, neurogenesis, synaptogenesis, and the prevention of amyloid fibrillation and neuronal injury. Several in vitro, preclinical, and clinical studies sugg …
Accumulating evidence supports the beneficial roles of natural-based products in brain function, neurotransmission, neurogenesis, synaptogen …
Aqueous-ethanol extracts of some South African seaweeds inhibit beta-amyloid aggregation, cholinesterases, and beta-secretase activities in vitro.
Olasehinde TA, Olaniran AO, Okoh AI. Olasehinde TA, et al. J Food Biochem. 2019 Jul;43(7):e12870. doi: 10.1111/jfbc.12870. Epub 2019 Apr 26. J Food Biochem. 2019. PMID: 31353743
Our findings suggest that the seaweed extracts are potential sources of lead compounds and novel inhibitors of beta-amyloid aggregation, beta-secretase, and cholinesterases for the management of Alzheimer's diseases. ...They are commonly used as functi …
Our findings suggest that the seaweed extracts are potential sources of lead compounds and novel inhibitors of beta-amyloid ag …
Capsicum annuum var. grossum (Bell Pepper) Inhibits beta-Secretase Activity and beta-Amyloid(1-40) Aggregation.
Ogunruku OO, Oboh G, Passamonti S, Tramer F, Boligon AA. Ogunruku OO, et al. J Med Food. 2017 Feb;20(2):124-130. doi: 10.1089/jmf.2016.0077. Epub 2017 Jan 18. J Med Food. 2017. PMID: 28098506
The deposition of amyloid protein as senile plaques is the major signature of Alzheimer's disease (AD). ...Thereafter, the inhibitory potentials of the extracts on beta-secretase and beta-amyloid(1-40) aggregation were determined. ...
The deposition of amyloid protein as senile plaques is the major signature of Alzheimer's disease (AD). ...Thereafter, the inh …